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超声造影结合增强 CT对胆囊占位性病 变的诊断价值分析*

作者:闫慧霞

所属单位:河南省人民医院省直第一医院超声 科 (河南 郑州 450000)

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摘要

目的 探讨超声造影结合增强CT 对胆囊占位性病变的诊断价值。方法 选 取2017年5月至2018年2月因胆囊占位性 病变入院手术治疗患者120例,所有病例 均经手术病理证实,对患者进行超声造 影与增强CT扫描检查,以病理结果为金 标准,分析其病变类型的诊断准确率。 结果 超声造影胆囊占位性病变类型诊断 结果与病理结果比较,胆囊息肉诊断准确 率92.59%,胆囊腺肌增生症诊断准确率 80.00%,胆囊癌诊断准确率82.76%;增强 CT胆囊占位性病变类型诊断结果与病理结 果比较,胆囊息肉诊断准确率88.89%,胆 囊腺肌增生症诊断准确率70.00%,胆囊癌 诊断准率89.66%;超声造影结合增强CT胆 囊占位性病变类型诊断结果与病理结果比 较,胆囊息肉诊断准确率97.53%,胆囊腺 肌增生症诊断准确率90.00%,胆囊癌诊断 准率96.55%;超声造影结合增强CT判断肿 瘤可显著提高胆囊占位性肿瘤病变鉴别准 确率,检测准确度、特异度、灵敏度、阳 性预测值、阴性预测值均高于单独超声造 影与单独增强CT扫描;增强CT检测胆囊癌 病变分型诊断准确性高于超声造影,联合 检测结果基本与增强CT扫描结果一致。结 论 超声造影结合增强CT对胆囊占位性病 变诊断中具有积极作用,可显著提高诊断 准确率。

Objective To explore the diagnostic value of contrast-enhanced ultrasound combined with enhanced CT in the diagnosis of gallbladder space-occupying lesions. Methods 120 cases of patients admitted to our hospital from May 2017 to February 2018 for gallbladder space-occupying lesions were enrolled. All cases were confirmed by surgical pathology, and patients were given contrast-enhanced ultrasound and enhanced CT scan, and the results and pathological results were taken as gold standards to analyze the diagnostic accuracy of lesion types. Results The diagnostic accuracy of gallbladder polyps was 92.59%, and the diagnostic accuracy of gallbladder adenomyomatosis was 80.00% and the diagnostic accuracy of gallbladder cancer was 82.76% by contrast-enhanced ultrasound results and pathological results of gallbladder space-occupying lesions types. The diagnostic accuracy of gallbladder polyps was 88.89%, and the diagnostic accuracy of gallbladder adenomyomatosis was 70.00% and the diagnostic accuracy of gallbladder cancer was 89.66% by enhanced CT results and pathological results of gallbladder spaceoccupying lesions types. The diagnostic accuracy of gallbladder polyps was 97.53%, and the diagnostic accuracy of gallbladder adenomyomatosis was 90.00% and the diagnostic accuracy of gallbladder cancer was 96.55% by contrast-enhanced ultrasound and enhanced CT results and pathological results of gallbladder space-occupying lesions types. Contrastenhanced ultrasound combined with enhanced CT could significantly improve the accuracy of gallbladder-occupying tumor lesions, and the detection accuracy, specificity, sensitivity, positive predictive value and negative predictive value were higher than those of single contrast-enhanced ultrasound or single enhanced CT scan. The diagnostic accuracy of enhanced CT for gallbladder cancer classification was higher than that of contrast-enhanced ultrasound, and the combined detection results were basically consistent with enhanced CT scan results. Conclusion Contrast-enhanced ultrasound combined with enhanced CT has a positive effect on the diagnosis of gallbladder space-occupying lesions, and it can significantly improve the diagnostic accuracy.

【关键词】超声造影;增强CT;胆囊占位 性病变;诊断价值

【中图分类号】R735.8;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2019.05.031

前言

胆囊占位性病变主要涉及胆囊息肉样病变和胆囊肿瘤,分为良性 和恶性两种。胆囊良性病变有胆固醇性息肉、炎性息肉、胆囊腺肌样 增生、胆囊腺瘤等,恶性病变主要有原发性胆囊癌[1-2]。目前,临床主 要使用超声对胆囊占位性疾病进行诊断及鉴别诊断,然而常规二维超 声检查对胆囊良恶性鉴别诊断存在一定的困难,易受到肿块大小、仪 器敏感性、患者配合程度及操作者技术的影响[3]。超声造影(CEUS)是 近年来应用到胆囊占位性病变中的一项超声显像新技术,可实时显示 病变内的血流信号[4]。增强CT扫描根据病灶区域组织密度的差异进行 成像,通过推注造影剂作强化扫描,可同时观察病灶不同期相血供来 源和血供特点[5]。为进一步提高胆囊占位性病变诊断准确性,本研究 探讨超声造影联合增强CT扫描对胆囊占位性病变的诊断价值,报告如 下。