简体中文

论著-头颈部

超声联合MSCT诊断 早期肝癌的临床研 究

作者:郑 芳 孔丽茹 范会军 王海燕 张 凯

所属单位:新乡医学院第一附属医院超声科 (河南 新乡 453000)

PDF

摘要

目的 探究超声联合多排螺旋 CT(MSCT)对早期肝癌诊断的临床价值。方 法 回顾性分析80例早期肝癌患者临床资 料,以细针穿刺活检术或数字血管减影 造影术(DSA)检查结果为“金标准”,分 析超声、MSCT及联合检查对病变特征[假 包膜、肝内动静脉瘘(AVF)、门静脉癌栓 (PVTT)]诊断效果差异。结果 联合检查诊 断假包膜、PVTT准确度均明显高于单纯超 声、MSCT检查,诊断AVF准确度则明显高 于单纯超声检查,差异均有统计学意义(P <0.05);联合检查在诊断病变特征方面 与对应“金标准”一致性均属良好(κ> 0.70)。结论 超声联合MSCT应用于早期肝 癌诊断中可获取较多病变特征信息,临床 应用价值较高。

Objective To explore the clinical value of ultrasound combined with multislice spiral CT (MSCT) in the diagnosis of early liver cancer. Methods The clinical data of 80 patients with early liver cancer were retrospectively analyzed. The results of fine needle aspiration biopsy or digital subtraction angiography (DSA) were used as gold standard to analyze the diagnostic effects of ultrasound, MSCT and combined examination on the lesion features [pseudocapsule, arterio-venous fistula (AVF), portal vein tumor thrombus (PVTT)]. Results The accuracies of combined diagnosis in the diagnosis of pseudocapsule and PVTT were significantly higher than those of simple ultrasound and MSCT, and the accuracy in the diagnosis of AVF was significantly higher than that of simple ultrasound (P<0.05). The consistency of combined diagnosis in the diagnosis of lesion features was good with corresponding gold standard (κ>0.70). Conclusion Ultrasound combined with MSCT can obtain more lesion features in the diagnosis of early liver cancer, and it has high clinical application value.

【关键词】超声;多排螺旋CT;早期肝癌

【中图分类号】R735.7;R445.1;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2019.05.030

前言

原发性肝癌作为世界范围内最常见恶性肿瘤之一,已成为既肺癌 之后男性癌症患者死亡的最主要诱因。早期肝癌临床表现不甚明显, 但发展较为迅速,且因恶性程度较大,周围浸润及远处转移几率较 高[1],故准确诊断与及时治疗是改善肝癌患者预后与延长生存期的关键 所在。目前临床常见用于诊断肝癌的无创方法主要包括超声、多排螺 旋CT(MSCT)等影像学途径,其中超声简便易行且成本低廉,借助多普 勒血流成像技术可实现对病灶血流情况的观察,而MSCT则可凭借其高 分辨率对较小病灶进行全面分析,既往关于二者已有较多对比研究, 通常认为CT诊断准确性较好而超声检出率较高[2-4],故存在一定争议。 基于此,本研究旨在探索超声与MSCT联合诊断应用于肝癌的临床价 值,现将取得成果报道如下。