目 的 分析术前多层螺旋 CT(multisliecs helieal CT，MSCT) 联合血清鳞状细胞癌抗原 ( s g u a m o u s cell carcinoma，SCC)、糖类抗原19- 9(carbonhydrate antigen 19-9， CA19-9)、癌胚抗原(carcino-embryonic antigen，CEA)检查对诊断食管癌的临 床价值。方法 选取我院收治的76例疑似 食管癌患者，术前均行MSCT与血清SCC、 CA19-9、CEA检查，以病理结果为“金 标准”，比较单纯MSCT与MSCT联合血清 SCC、CA19-9、CEA检查准确性、特异度、 灵敏度。结果 病理检查显示，食管癌 68例，非食管癌8例；MSCT诊断灵敏度 85.29%，特异度75.00%，准确性84.21%， Kappa值0.42；MSCT联合血清SCC、 CA19-9、CEA诊断灵敏度97.06%，特异度 87.50%，准确性96.05%，Kappa值0.80； MSCT联合血清SCC、CA19-9、CEA诊断食管 癌准确性与灵敏度明显高于单纯MSCT(P ＜0.05)。结论 术前MSCT联合血清SCC、 CA19-9、CEA检查，可有效提高食管癌诊 断灵敏度与准确性，具有较高应用价值。

Objective To analyze the clinical value of preoperative multislice helice CT (MSCT) combined with serum squamous cell carcinoma (SCC), carbohydrate antigen 19-9 (CA19-9) and carcino-embryonic antigen (CEA) examination in the diagnosis of esophageal cancer. Methods 76 patients with suspected esophageal cancer admitted to the hospital were enrolled. MSCT and serum SCC, CA19-9 and CEA examination were performed before operation. Taking the pathological results as the golden standard, the accuracy, specificity and sensitivity of MSCT and MSCT combined with serum SCC and CA19-9 and CEA examination were compared. Results Pathological examination results showed that there were 68 cases with esophageal cancer and 8 cases without esophageal cancer. The diagnostic sensitivity, specificity, accuracy and the Kappa value of MSCT were 85.29%, 75.00%, 84.21% and 0.42, respectively. The above 4 indexes of MSCT combined with serum SCC, CA19-9 and CEA were 97.06%, 87.50%, 96.05% and 0.80, respectively. The accuracy and sensitivity of MSCT combined with serum SCC, CA19-9 and CEA in the diagnosis of esophageal cancer were significantly higher than those of MSCT (P<0.05). Conclusion Preoperative MSCT combined with serum SCC, CA19-9 and CEA examination can effectively improve the diagnostic sensitivity and accuracy for esophageal cancer, which has relatively higher application value.