简体中文

论著-头颈部

CT血管成像联合12 导联动态心电图在 冠心病诊断中的应 用

作者:吴志红1 杨 瑞2

所属单位:1.河南省胸科医院心肺功能科 (河南 郑州 450000) 2.河南省胸科医院影像科 (河南 郑州 450000)

PDF

摘要

目的 探究CT血管成像联合12导 联动态心电图(AECG)对冠心病的诊断价 值。方法 选择2015年7月至2018年1月我 院心血管内科收治的疑似冠心病的患者92 例作为研究对象,所有患者均行多层螺旋 CT及12导联AECG检查,并经冠状动脉造影 (CAG)证实,以CAG诊断结果为金标准,计 算MSCT、12导联AECG及两者联合诊断冠心 病的灵敏度、特异度、阳性预测值、阴 性预测值及准确率。结果 MSCT诊断冠心 病的灵敏度、特异度、准确度、阳性预测 值、阴性预测值分别为86.79%、87.18%、 86.95%、90.19%、82.93%;AECG诊断冠心 病的诊断灵敏度、特异度、准确度、阳 性预测值、阴性预测值分别为79.24%、 84.61%、81.52%、87.50%、75.00%;两者 联合诊断准确度显著高于MSCT及12导联 AECG,差异具统计学意义(P<0.05)。结论 CT血管成像联合12导联动态心电图可提高 冠心病诊断准确性,可在临床上推广使 用。

Objective To investigate the diagnostic value of CT angiography combined with 12-lead dynamic electrocardiogram (AECG) for the diagnosis of coronary heart disease. Methods A total of 92 patients with suspected coronary heart disease in our department from July 2015 to January 2018 were selected. All patients underwent multislice spiral CT and 12-lead AECG, confirmed by coronary angiography (CAG), taking CAG diagnosis results as the gold standard,the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of coronary heart disease by MSCT, 12-lead AECG and their combined diagnosis were calculated. Results The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of coronary heart disease by MSCT diagnosis were 86.79%, 87.18%, 86.95%, 90.19% and 82.93%, respectively, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of coronary heart disease by AECG diagnosis were 79.24%, 84.61%, 81.52%, 87.50%, and 75.00%, respectively. The combined diagnosis accuracy was significantly higher than that of MSCT and 12-lead AECG(P<0.05). Conclusion CT angiography combined with 12- lead dynamic electrocardiogram can improve the diagnostic accuracy of coronary heart disease and has potential to be promoted clinically.

【关键词】CT血管成像;12导联动态心电 图;冠心病;诊断价值

【中图分类号】R541.4

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2019.05.025

前言

冠心病是造成发达国家成人死亡的重要原因,我国冠心病发病率 虽低于发达国家,但发病率也呈逐年上升趋势,给社会带来巨大的经 济负担,提高冠心病的早期诊断效率并进行积极干预具有重要的临床 意义[1]。冠状动脉造影(CAG)为诊断冠状动脉狭窄的金标准,但其有创 性、风险性及较高的成本使其在冠心病筛查中难以普及,探究高效、 无创性的检查方式是影像医学研究的重点及难点[2]。CT是临床应用最 为广泛的影像学检查方法,在诸多器官及疾病中均具有一定的诊断价 值,在冠心病诊断方面,CT血管成像可通过注射造影剂观察冠状动脉 病变情况,具有无创、安全、快速等特点,是一种较为理想的检查方 式[3]。动态心动图(AECG)是一种通过监测ST段移位,连续记录患者心 电信号,借助计算机分析获取诊断依据的无创性诊断方法,近年来新 导联的应用使ST段记录更为准确,更能准确判断患者心肌缺血[4]。目 前CTA与AECG对冠心病的诊断价值已有诸多报道,但两者联合用于冠心 病的诊断尚待研究证实。本研究将多层螺旋CT及12导联动态心电图联 合用于冠心病的诊断,分析其诊断价值,旨在为临床诊断方式的选择 提供参考。现报道如下。