摘要
目的 探讨PET/CT在(鳞癌、腺 癌、小细胞肺癌)肺癌不同病理分型方面 的应用。方法 选取我院2016年1月至2018 年1月的198例肺癌患者进行研究,以手 术病理检查为金标准,采用PET/CT检查 不同病理分型的肺癌,探讨其诊断准确 性。结果 病理检查的鳞癌、腺癌、小细 胞肺癌分别为80例(40.0%)、70例(35.4%) 和48例(24.2%),PET/CT检查的鳞癌、腺 癌、小细胞肺癌分别为80例(40.0%)、 69例(34.8%)和46例(23.2%),准确率为 98.5%。鳞癌的PET/CT表现为肺内团块状 密度增高影,边界较清,边缘可见浅分 叶,病变与胸膜粘连,可见胸膜凹陷征, PET示放射性摄取增高,平均SUVmax为 30.6。腺癌的PET/CT表现为肺内团片状密 度增高影,边界欠清,形态欠规则,PET 示放射性摄取增高,平均SUVmax:12.1。 小细胞肺癌的PET/CT表现为肺门及纵隔内 团块状密度增高影,形态欠规则,PET示 放射性摄取增高,平均SUVmax:9.5。结 论 PET/CT有助于准确诊断不同病理分型 (鳞癌、腺癌、小细胞肺癌)的肺癌,而且 不同病理分型的肺癌PET/CT表现存在明显 不同。
Objective To study the application of PET/CT in lung cancer with different pathological types (squamous cell carcinoma, adenocarcinoma, small cell lung cancer). Methods A total of 198 patients with lung cancer from January 2016 to January 2018 were studied. According to the standard of operation and pathology, the characteristics and accuracy of different types of lung cancer were examined by PET/CT. Results The pathological examination of squamous cell carcinoma, adenocarcinoma and small cell lung cancer were 80 cases (40.0%), 70 cases (35.4%) and 48 cases (24.2%) respectively. And 80 cases (40.0%) of squamous cell carcinoma, 69 cases (34.8%) of adenocarcinoma and 46 cases (23.2%) of small cell lung cancer were performed by PET/CT, respectively. The accuracy rate was 98.5%. The PET/CT features of squamous cell carcinoma were as follows: high density mass located at the upper lobe of lung, with clear boundary, superficial lobes and pleural adhesion, and pleural indentation was seen. PET showed that the radioactivity uptake was increased with the average SUVmax was 30.6. The PET/ CT findings of adenocarcinoma included that the mass located at the upper lobe of the lung, with unclear boundary, and irregular shape, PET showed that the uptake of PET/ CT was increased with the mean SUVmax was 12.1, The PET/CT findings of small cell lung cancer including that a increased density mass located in hilum and mediastinum, with the uptake of PET/CT increased and the mean SUVmax was 9.5. Conclusion The PET/CT findings of lung cancer helps to the diagnosis of pathological types (squamous cell carcinoma, adenocarcinoma and small cell lung cancer) . The PET/CT findings of the lung cancer with different pathological types are obviously different.
【关键词】PET/CT;鳞癌;腺癌;小细胞 肺癌;准确性
【中图分类号】R734.2
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.05.013
前言
肺癌是一种恶性肿瘤,临床死亡率较高,资料[1]显示肺癌发病隐 匿、早期无明显症状表现,大多数患者确诊时已经到了肺癌晚期,因 此对患者进尽早准确诊断并及时治疗,有助于减少死亡率。对肺癌的 诊断方法有内镜检查(纤维支气管镜检查、经纤维支气管镜引导透壁穿 刺纵隔淋巴结活检术、胸腔镜检查等)、影像学检查(胸部X线、胸部 CT、B型超声、MRI、骨扫描、PET-CT等),关于PET-CT诊断肺癌的研 究比较多,主要用于对肺癌的分期、转移、临床疗效评价等[2-4],但是 关于PET-CT肺癌病理分型的应用未见详细报道,因此本研究通过对不 同病理分型(鳞癌、腺癌、小细胞肺癌)的肺癌进行病理分析,并采用 PET-CT检查,旨在说明PET-CT在不同病理分型肺癌的应用价值。
中国CT和MRI杂志
第17卷, 第 5 期
2019年05月
相关文章