摘要
目的 研究前路椎体次全切除钛 笼钛板内固定术(ACCF)与颈椎后路微型钛 板内固定结合单开门椎管成形术(ELAP)治 疗多节段脊髓型颈椎病(MCSM)的近期效果 及影像学变化。方法 回顾性分析我院82 例MCSM手术治疗患者临床资料,根据手术 方式不同分为ACCF(n=35)和ELAP(n=47) 两组,分析两组手术相关指标及手术前 后颈部疼痛VAS评分、JOA评分变化,采 用两组术前及术后6个月时X线平片和CT 图像计算颈椎曲度、椎管矢状径及颈椎 活动度并进行比较。结果 ACCF组手术时 间长于ELAP组,术中出血量、术后引流 量及平均住院时间少于ELAP组,差异有 统计学意义(P<0.05);术后6个月时,两 组VAS评分明显降低(P<0.05),JOA评分 明显升高(P<0.05),且两组差异无统计 学意义(P>0.05);两组颈椎曲度及活动 度明显降低(P<0.05),椎管矢状径明显 增加(P<0.05),且ACCF组颈椎曲度及活 动度高于ELAP组,椎管矢状径低于ELAP 组,差异有统计学意义(P<0.05);ACCF组 和ELAP组并发症发生率分别为25.71%和 29.79%(P>0.05)。结论 ACCF和ELAP治疗 MCSM均可有效缓解颈部疼痛,改善颈椎神 经功能,其中ACCF对患者创伤较小,有利 于促进患者术后康复并减少颈椎曲度及活 动度丢失,而ELAP则可扩大脊髓活动空 间,能更有效地解除脊髓压迫。
Objective To study the short-term effects and imaging changes of anterior cervical corpectomy and fusion (ACCF) and posterior cervical micro-titanium plate fixation combined with expansive laminoplasty (ELAP) in the treatment of multilevel cervical spondylotic myelopathy (MCSM). Methods The clinical data of 82 patients with MCSM surgery in our hospital were retrospectively analyzed. The patients were divided into ACCF group (n=35) and ELAP group (n=47) according to different surgical methods. Surgery-related indexes and neck pain VAS score and JOA score before and after surgery were analyzed in the two groups. X-ray plain film and CT images were used to calculate and compare the cervical curvature, sagittal diameter of spinal canal and cervical vertebra activity before surgery and at 6 months after surgery. Results The operative time in ACCF group was longer than that in ELAP group, and the intraoperative blood loss, postoperative drainage volume and average hospital stay were less than those in ELAP group (P<0.05). At 6 months after surgery, the VAS scores in the two groups were significantly decreases (P<0.05) while the JOA scores were significantly increased (P<0.05), and the differences between the two groups were not statistically significant (P>0.05). The cervical curvature and activity in the two groups were significantly decreased (P<0.05), and the sagittal diameter of spinal canal was increased significantly (P<0.05), and the cervical curvature and activity in ACCF group were higher than those in ELAP group, and the sagittal diameter of spinal canal was lower than that in ELAP group (P<0.05). The incidence rate of complications was 25.71% in ACCF group and 29.79% in ELAP group (P>0.05). Conclusion Both ACCF and ELAP can effectively relieve neck pain and improve cervical nerve function in the treatment of MCSM. Among them, ACCF has less trauma to patients, and it is beneficial to promote postoperative rehabilitation and reduce loss of cervical curvature and activity. And ELAP can enlarge activity space of spinal cord, and it can more effectively relieve spinal cord compression.
【关键词】前路椎体次全切除钛笼钛板内 固定术;单开门椎管成形术
【中图分类号】R651.2
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2019.05.012
前言
多节段脊髓型颈椎病(multilevel cervical spondylotic myelopathy,MCSM)早期多采用保守治疗缓解症状,但脊髓压迫症状明 显者需行手术治疗及时切除压迫以避免造成截瘫等严重并发症,现阶 段临床对MCSM手术方式选择尚存有争议,单纯前路病理改变可采用前 路减压术治疗,其中前路椎体次全切除钛笼钛板内固定术(anterior cervical corpectomy and fusion,ACCF)在重建颈椎正常生理曲度 方面优势明显,但常难以解决椎管狭窄问题,且循证医学证据显示 多节段颈椎病变更适合进行后路手术,后路颈椎单开门椎管成形术 (expansive open-door laminoplasty,ELAP)自1970年由日本学者首 次开展以来已被公认为MCSM最有的手术方案,且近年来微型钛板内固 定的发现和应用有效解决了ELAP术后顽固轴性症状(axial symptoms, AS)及椎板再关门等问题,使其临床疗效明显提升[1-4]。目前国内外关 于MCSM前后路手术方案治疗效果比较的报道较少,本文主要比较ACCF 及ELAP治疗MCSM近期效果及影像学变化特征,为临床选择合理手术方案提供参考依据。
中国CT和MRI杂志
第17卷, 第 5 期
2019年05月
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