简体中文

论著-头颈部

三种影像学方法(X 线、CT和MRI)诊断 痛风性关节炎的结 果分析

作者:张 斌1 张晓丽2 宋春青3 郭彩虹3 任阿红1

所属单位:1.北京市大兴区人民医院放射科 (北京 102600) 2.北京市大兴区人民医院骨科 (北京 102600) 3.北京市大兴区人民医院肿瘤内科 (北京 102600)

PDF

摘要

目的 比较X线、CT和MRI三种影 像学检查方法在痛风性关节炎中的诊断 价值。方法 收集我院内科近一年(2017 年3月-2018年3月)经临床证实的116例痛 风性关节炎患者的影像学资料(X线、CT 和MRI),比较三种影像检查对通风性关 节炎的检出率及影像学表现。结果 116 例患者共确诊病变关节241个,X线、CT 和MRI对痛风性关节炎的检出率分别为 53.11%(128/241)、73.86%(178/241)、 88.38%(213/241);X线对病变关节中的痛 风性结节、关节面下囊变、软组织肿胀的 检出率显著少于CT、MRI(P<0.05);CT对 病变关节中的痛风性关节、关节面下囊变 的检出率与MRI无显著差异(P>0.05),CT 对病变关节中关节积液、软组织肿胀的检 出率显著少于MRI(P<0.05)。结论 X线、 CT和MRI三种影像学检查方法对痛风性关 节炎均具有较高的诊断价值,与X线及CT 检查相比,MRI在痛风性关节炎中的诊断 价值更高。

Objective To compare the diagnostic value of X-ray, CT and MRI for the diagnosis of gouty arthritis. Methods The imaging data (X-ray, CT and MRI) of 116 patients with gouty arthritis confirmed by clinical practice who were treated in internal medicine department of the hospital from March 2017 to March 2018 were collected. The detection rate and imaging findings were compared among the three imaging methods. Results A total of 241 affected joints were diagnosed in 116 patients. The detection rates of gouty arthritis by X-ray, CT and MRI were 53.11% (128/241), 73.86% (178/241) and 88.38% (213/241) respectively. The detection rates of gout nodules, articular sub-capsular changes and soft tissue swelling in the affected joints by X-ray were significantly less than those by CT and MRI (P<0.05). There was no significant difference in the detection rates of gouty joints and articular sub-capsular changes between CT and MRI (P>0.05), and the detection rates of joint effusion and soft tissue swelling by CT were significantly less than those by MRI (P<0.05). Conclusion Three imaging methods of X-ray, CT and MRI all have high clinical value for the diagnosis of gouty arthritis. MRI has higher diagnostic value in gouty arthritis compared with X-ray and CT.

【关键词】痛风性关节炎;X线;CT; MRI;诊断价值

【中图分类号】R684.3;R814.41

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2019.01.042

前言

痛风性关节炎(Gouty Arthritis,GA)是指长期嘌呤代谢紊乱及 血尿酸排泄减少所引起的一组异质性、代谢性疾病[1]。尿酸盐易沉积 在关节囊、滑囊、软骨、骨质及其他组织中导致结缔组织炎症反应 及病理改变[1]。痛风性关节炎发病有遗传倾向,但发病原因并不十分 明确,常见于中老年人群,男性多发[2]。根据临床表现,GA通常分为 急性关节炎期、间歇期、慢性关节炎期[1]。未接受及时合理治疗的患 者平均11年左右会由急性关节炎期进展到慢性关节炎期,出现关节 畸形、关节脱位、运动障碍等,晚期可继发高血压、大动脉粥样硬 化、心肌梗死等严重并发症,甚至危及患者生命安全[2],且近年来研 究发现GA在年轻人中的发病率逐渐升高[3],故提高GA的临床检出率对 疾病的防治至关重要。临床常用的检查方法中影像学检查广泛且价 值较高,为研究X线(X-ray)、CT和磁共振成像(Magnetic Resonance Imaging,MRI)三种影像学方法对GA的诊断效能,现对我院近一年收治 的116例患者的影像资料进行分析,以期提高对GA影像学征象的认识, 为临床该疾病的诊断及治疗提供可靠的依据。