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胃肠道间质瘤患者 超声和MSCT征象特 点分析

作者:廖 月

所属单位:河南省省直第二医院超声科 (河南 郑州 450000)

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摘要

目的 分析胃肠道间质瘤(GIST) 患者超声和多层螺旋电子计算机断层扫描 (MSCT)征象特点。方法 回顾性分析2016 年3月-2017年12月我院接受超声及MSCT检 查且经手术病理(金标准)诊断的68例单 发GIST患者临床资料。比较超声及MSCT与 金标准定位诊断情况差异,并分析2种检 查方法对不同恶性危险度GIST的征象特 点。结果 68例单发GIST病例中肿瘤位于 胃部41例(60.29%),小肠19例(27.94%), 结直肠8例(11.77%);其中极低危5例 (7.35%),低危11例(16.18%),中危14例 (20.59%),高危38例(55.88%)。MSCT定 位诊断准确率明显高于超声(P<0.05)。 MSCT及超声对不同危险度GIST的征象特点 均显示,危险度越高者肿瘤直径越大(P <0.05),且形态不规则及边界模糊发生 率越高(P<0.05);但不同危险度GIST的 MSCT钙化及淋巴结转移情况、超声回声及 血流情况比较,差异无统计学意义(P> 0.05)。结论 MSCT及超声均能通过评估肿 瘤直径、形态与边界情况以判断GIST的恶 性危险度,而MSCT能更准确地判定GIST的 发生部位,于后续临床治疗更有利。

Objective To analyze the signs features of ultrasound and multi-slice spiral computed tomography (MSCT) imaging in patients with gastrointestinal stromal tumors (GIST). Methods The clinical data of 68 patients with single GIST diagnosed by surgical pathology (gold standard) underwent ultrasound and MSCT from March 2016 to December 2017 in our hospital were analyzed retrospectively. The differences in the diagnosis of ultrasound and MSCT were compared, and the features of two kinds of examination methods of different malignant risk were analyzed. Results A total of 68 single GIST cases, 41 cases (60.29%) located in stomach, 19 cases (27.94%) in small intestine and 8 cases (11.77%) in rectum. Five cases (7.35%) were extremely low risk, 11 cases (16.18%) were low risk, 14 cases(20.59%) were middle risk and 38 cases (55.88%) was high risk. The accuracy rate of MSCTwas significantly higher than that of ultrasound (P<0.05). The signs features of MSCT and ultrasound towards different risk GIST showed that the higher the risk of GIST was, the larger the tumor diameter was (P<0.05) and the higher the incidence rates of irregular shape and blurring boundary were (P<0.05). But there was no statistical difference in the MSCT calcification and lymph node metastasis between ultrasound and MSCT, ultrasonic echo and blood flow in GIST with different risk degrees (P>0.05). Conclusion MSCT and ultrasound can judge the malignant risk of GIST by evaluating the tumor diameter, shape and boundary, and MSCT can determine the location of GIST more accurately and it is more favorable for the follow-up clinical treatment.

【关键词】胃肠道间质瘤;MSCT;超声; 定位诊断;危险度分级

【中图分类号】R722.15+2

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2019.01.031

前言

胃肠道间质瘤(GIST)为胃肠道常见的间叶源性肿瘤,具有恶性潜 能、非定向分化的特点,临床对其良、恶性的诊断标准一直存在争 议[1]。既往常将肿瘤直径≥10cm、形态不规则、分叶样生长等作为 GIST的恶性征象,但目前临床工作中也能发现体积较小的看似良性 GIST出现远处转移[2]。因此,美国国立卫生院(NIH)也根据GIST的肿瘤 直径及核分裂数,将其分为极低危险度、低危险度、中危险度及高危 险度,以指导临床治疗方案及辅助评估患者预后[3]。然而,此危险度 分级多通过术后病理学检查结果判断,而在术前难以做出相应诊断, 故寻找术前有效的危险度评估方法,对临床选择合适的治疗方案非常 重要[4]。超声及多层螺旋电子计算机断层扫描(MSCT)均为临床常用影 像学检查方法,在肿瘤的术前诊断中应用价值较高[5]。但鲜少有学者 分析上述2种检查方法对不同危险度GIST的征象特点。基于此,本研究 回顾性分析2016年3月-2017年12月我院接受超声及MSCT检查且经手术 病理诊断的68例单发GIST患者临床资料,以评估该2种检查方法的诊断 价值,现报告如下。