摘要
目的 采用64层螺旋CT对肝硬化 患者及正常对照组肝脏体积进行测量,探 讨肝硬化时肝脏体积变化规律与其肝硬化 严重程度之间的关系。方法 对47例经临 床资料证实肝硬化患者进行肝功能ChildPugh分级,其中A级19例,B级20例,C级 8例,正常对照组200例行64层螺旋CT上 腹部增强扫描,并测量身高、体重,采 用测量软件分别测量肝脏体积及标准化 肝脏体积。结果 正常对照组肝脏体积分 别为:LV男(1259.91±303.35)cm3 ,LV女 (1146.29±291.59)cm3 ;标准化肝脏体积 分别为:LV男(687.09±138.90)cm3 ;LV女 (653.14±153.65)cm3 。肝硬化组与正常 对照组比较,除Child A组均高于正常对 照组外,余各级体积均低于正常对照组, 且两两比较有统计学差异(P<0.05)。结论 64层螺旋CT能客观测量肝脏体积,肝硬化 时肝脏的体积变化与疾病的严重程度相 关,有助于肝储备功能的客观评价。
Objective To measure the liver volume with 64slices helical CT between hepatic cirrhosis patients and normal control group, and evalute the relationship between the change of liver volme and Child-pugh degree in the hepatic cirrhosis patients. Methods A total of 47 hepatic cirrhosis cases which diagnosedby clinic,19 cases were Child A, 20 cases were Child B, 8 cases were Child C, and 200 case were enrolled into the control group. Use the CT measurement software to measure the liver volume. Results The whole liver volume measurement in males and females in control group were (1259.91±303.35)cm3 and (1146.29±291.59)cm3 respectively; Standard liver volume were (687.09±138.90)cm3 and (653.14±153.65)cm3 respectively. The LV in Child B and C of hepatic cirrhosis patients were lower than that of control group, however in the liver volume of Child A were larger than the other groups. Conclusion The 64 slice helical CT can measure the hepatic volume. The changes of the liver volume were strongly correlated with the severity of hepatic cirrhosis, which is helpful for the objective evaluation of liver reserve function
【关键词】肝脏体积;肝硬化;体表面 积;标准肝脏体积
【中图分类号】R575.2;R814.42
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2019.01.028
前言
肝硬化是慢性肝脏疾病长期发展的结果,肝硬化程度直接对患者 健康甚至生命产生威胁[1]。流行病学资料显示,慢性乙型肝炎是中国 肝硬化的主因[2],但近年来,随着人们饮食结构的改变,酗酒人群的 数量不断增加,酒精性肝病的发病率也呈上升趋势,成为导致肝损伤 的重要病因[3]。目前临床主要依赖肝活检病理检查来诊断肝硬化并确 定其程度,尚缺乏有效的无创性诊断方法。肝硬化阶段,随着肝内胶 原沉积,肝小叶结构改变,使肝脏体积发生改变,肝体积改变能够 反映肝脏实质细胞数量变化[4]。肝体积的准确测量已成为肝脏疾病诊 断、治疗方法的选择以及预后评估的一项重要指标,本文采用MSCT测 量大样本肝硬化患者,对照正常志愿者肝脏体积,评价肝硬化患者肝 体积变化与病变的严重程度之间的关系。
中国CT和MRI杂志
第17卷, 第 1 期
2019年01月
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