目的 探讨磁共振成像(MRI)结合 正电子发射断层显像(PET-CT)在脑胶质瘤 术前诊断中的价值。方法 对我院神经外 科近两年(2016年3月-2018年3月)收治的 84例临床高度怀疑为脑胶质瘤患者术前 行MRI及PET-CT检查，以术后病理检查结 果为参考标准，评估单独MRI及MRI结合 PET-CT检查在脑胶质瘤术前诊断中的价 值。结果 84例患者术后病理证实为高级 别胶质瘤21例、低级别胶质瘤55例、脑胶 质瘤阴性8例，均为单发肿瘤；MRI对脑 胶质瘤术前诊断灵敏度、特异度、准确 性分别为96.05%(73/76)、100%(8/8)、 96.43%(81/84)，评估脑胶质瘤分级的准 确性为75.00%(57/76)，MRI结合PET-CT 对脑胶质瘤术前诊断的灵敏度、特异度、 准确性分别为98.69%(75/76)、100%、 98.81%(83/84)，评估脑胶质瘤分级的准 确性为93.42%(71/76)；MRI结合PET-CT对 脑胶质瘤术前评估的准确性显著优于单独 MRI检查(P<0.05)。结论 MRI结合PET-CT 对脑胶质瘤术前诊断的灵敏度、特异度和 准确率较高，可更准确评估肿瘤恶性程 度，提供脑胶质瘤更全面精确的信息，帮 助临床制定更科学合理的治疗方案，具有 较高的临床诊断价值。

Objective To explore the value of magnetic resonance imaging (MRI) combined with positron emission tomography (PET-CT) in the preoperative diagnosis of brain glioma. Methods A total of 84 cases of patients with high suspicion of brain glioma admitted to neurosurgery department of our hospital in the past two years (from March 2016 to March 2018) were given MRI and PET-CT before operation. The results of postoperative pathological examination were taken as reference to evaluate the value of separate MRI and MRI combined with PET-CT in the preoperative diagnosis of brain glioma. Results Postoperative pathology of 84 cases of patients confirmed 21 cases of highgrade glioma, 55 cases of low-grade glioma and 8 cases of negative glioma, and all were single tumors. The sensitivity, specificity and accuracy of MRI for preoperative diagnosis of brain glioma were 96.05% (73/76), 100% (8/8) and 96.43% (81/84) respectively, and the accuracy of glioma grading was 75.00% (57/76). The sensitivity, specificity and accuracy of MRI combined with PET-CT for preoperative diagnosis of brain glioma were 98.69% (75/76), 100% and 98.81% (83/84) respectively, and the accuracy of glioma grading was 93.42% (71/76). The accuracy of MRI combined with PET-CT was significantly better than that of MRI in the preoperative evaluation of glioma (P<0.05). Conclusion MRI combined with PET-CT has high sensitivity, specificity and accuracy in the preoperative diagnosis of glioma, and it can more accurately assess the degree of tumor malignancy, provide more comprehensive and accurate information of glioma, and help to formulate more scientific and reasonable treatment regimen in clinical practice, and it has a high clinical diagnostic value.