目的 观察磁共振动脉自旋标记 (3D-ASL)及磁共振弥散加权成像(DWI)在 急性缺血性脑卒中(CIS)患者中的临床应 用。方法 选取2017年1月-2018年4月我院 诊治的CIS患者共60例，另纳入30名健康 志愿者作为对照组，均进行3D-ASL及DWI 扫描，对比两种检查方式在CIS患者中的 应用价值。结果 诊断为右侧大脑半球急 性缺血性脑卒中患者共34例，表现为右 侧脑血流量(CBF)绝对值显著低于左侧， 两侧CBF绝对值均低于健康对照组，均有 统计学意义(P＜0.05)；诊断为左侧大脑 半球急性缺血性脑卒中患者共26例，表现 为两侧脑血流量(CBF)绝对值均低于健康 对照组，均有统计学意义(P＜0.05)。结 论 3D-ASL能够清楚显示CIS患者局部脑组 织缺血梗死病灶的血流动力学改变，结合 CBF值能更为客观的反应脑组织缺血梗死 灌注情况，为CIS的临床诊断提供重要依 据。

Objective To observe the clinical application of magnetic resonance arterial spin labeling (3D-ASL) and diffusion weighted imaging (DWI) in patients with acute cerebral ischemic stroke (CIS). Methods A total of 60 cases of CIS patients in our hospital from January 2017 to February 2018 were selected, and 30 healthy volunteers were enrolled as control group, and all of them were given 3D-ASL and DWI imaging scans respectively. The application value of the two methods in CIS patients was compared. Results In 34 patients with acute ischemic stroke on the right side, the absolute value of right cerebral blood flow (CBF) was significantly lower than that of the left side, and the absolute values of CBF on both sides were lower than those in healthy control group (P<0.05). In 26 patients with acute ischemic stroke on the left side, the absolute values of bilateral cerebral blood flow (CBF) were lower than those in healthy control group (P<0.05). Conclusion 3D-ASL can clearly show the hemodynamic changes of ischemic infarct lesions in patients with CIS, and combined with CBF value was more objective in responding to the ischemic infarction perfusion of brain tissue, and can provide an important basis for the clinical diagnosis of CIS.