简体中文

论著-头颈部

DWI联合MRCP对壶腹部梗阻性黄疸诊断价值的研究*

作者:陈永芊 敬文斌 张德军

所属单位:四川省德阳市第二人民医院(四川 德阳 618000)

PDF

摘要

目的探究弥散加权成像(DWI) 联合胰胆管水成像(MRCP)对壶腹部梗阻 性黄疸的诊断价值。方法 选择2015年2 月至2017年2月我院收治的62例因壶腹 部病变所致梗阻性黄疸患者作为研究对 象,30例患者行MRCP扫描,纳入对照 组;32例患者行MRCP联合DWI检查,纳 入观察组。分析所有病例的MRCP征象、 DWI图像质量及信号特征,与病理学检 查结果进行比较。结果 MRCP可清楚显 示胆管系统结构,恶性病变胆管表现为 “软藤样”扩张,DWI可见清晰肿块及胆 囊壁增生;良性病变表现为“枯枝样” 扩张,DWI无特殊征象;对照组总诊断 符合率为63.33%,观察组总诊断符合率 为93.75%,两组比较差异具统计学意义 (χ2 =6.907,P<0.05)。结论 MRCP联合 DWI对壶腹部梗阻性黄疸的诊断效能显著 优于单一MRCP诊断,临床上可将其作为 诊断工作中的参考方案。

Objective To explore the value of diffusion-weighted imaging (DWI) combined with magnetic resonance cholangiopancreatography (MRCP) in the diagnosis of ampullar obstructive jaundice. Methods A total of 62 patients with obstructive jaundice due to ampullar disease treated in the hospital from February 2015 to February 2017 were enrolled as the subjects, 30 patients were scanned by MRCP (the control group) and 32 patients were examined by MRCP and DWI (the observation group). The MRCP signs, DWI image quality and signal characteristics of all cases were analyzed and compared with the pathological examination results. Results MRCP could clearly show the structure of bile duct. The malignant diseased bile duct showed soft rattanlike dilation, and DWI showed clear masses and gallbladder wall hyperplasia. The benign lesion showed dry branch-like dilation. There was no special DWI images. The total diagnostic coincidence rates in the control group and the observation group were 63.33% and 93.75%, respectively (χ2 =6.907, P<0.05). Conclusion The diagnostic efficiency of MRCP combined with DWI for ampullar obstructive jaundice is significantly better than that of single MRCP diagnosis. It can be used as a reference scheme in clinical diagnosis.

【关键词】弥散加权成像;胰胆管水成像;壶腹部;梗阻性黄疸

【中图分类号】R735.8;R730.44

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.09.029

前言

梗阻性黄疸是临床常见疾病,其常见病因主要有结石、炎症及肿 瘤等,梗阻性黄疸的临床检查除临床病史、体征及实验室指标检测以 外,影像学检查是较为重要的能对梗阻部位及原因做出判断的检查方 式[1-2]。弥散加权成像(DWI)是目前唯一能反映活体组织功能状态的检 查方法,对于明确人体的生理活动及组织结构病理变化具有较好的 效果[3]。胰胆管水成像(MRCP)为无需造影剂、无放射损伤的无创性检 查,可显示梗阻部位及受累胆道的情况,临床研究证实,MRCP对肝外 胆管病变的诊断准确率与内镜逆行性胰胆管造影相当,对胆道结石的 诊断价值优于CT及B超[4]。但MRCP易受到胆汁高信号的影响,对于胆道 内气体、结石及血凝块等区分,需联合MRI平扫进行确诊[5]。本研究采 用MRCP联合高分辨率DWI对壶腹部梗阻性黄疸进行诊断,为临床梗阻性 黄疸的临床诊断提供参考。