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多层螺旋CT结合MRI对肺动脉栓塞的诊断价值*

作者:杨尊帅 胡秋根 杨少民 陈海雄 徐锦锋

所属单位:南方医科大学顺德医院(佛山市顺德区第一人民医院)(广东 顺德 528300)

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摘要

目的探究多层螺旋CT(MSCT)结 合磁共振成像(MRI)对肺动脉栓塞的诊断 价值。方法 选择我院2015年2月至2017年 8月收治的经影像学检查确诊为肺动脉栓 塞的66例患者作为研究对象,所有患者均 行MSCT及MRI扫描,并经数字减影血管造 影(DSA)及病理诊断进行确诊,由两位影 像学医师对MSCT及MRI图像进行分析,比 较MSCT、MRI及MSCT联合MRI诊断肺动脉栓 塞的效果。结果 66例患者MSCT诊断显示 受累的肺动脉为145支,MRI诊断受累肺动 脉为137支,MSCT联合MRI诊断显示受累的 肺动脉为154支,其中直接征象为肺动脉 内不同程度的充盈缺损;间接征象包括马 赛克征、肺动脉高压、胸腔积液、脑梗 死等;以DSA及病理诊断结果为金标准, MSCT、MRI及MSCT联合MRI诊断的灵敏度分 别为92.94%、87.82%及98.71%,组间比较 差异显著(P<0.05)。结论 MSCT联合MRI对 肺动脉栓塞诊断效果显著优于单一MSCT及 MRI诊断,临床上可根据将其作为肺动脉 栓塞诊断的参考。

Objective To explore the value of multi-slice spiral CT (MSCT) combined with magnetic resonance imaging (MRI) in the diagnosis of pulmonary embolism. Methods A total of Sixty-six patients with pulmonary embolism diagnosed by imaging examination in the hospital from February 2015 to August 2017 were selected as the study subjects. All patients underwent MSCT and MRI scans, and digital subtraction angiography (DSA) was performed for confirmed diagnosis. Images of MSCT and MRI were analyzed by two imaging physicians. The effects of MSCT, MRI and MSCT combined with MRI in diagnosis of pulmonary embolism were compared. Results MSCT showed 145 involved pulmonary arteries while MRI showed 137 pulmonary arteries in 66 patients. MSCT combined with MRI showed 154 pulmonary arteries. The direct signs included different degrees of filling defects in pulmonary arteries, while indirect signs included mosaic sign, pulmonary hypertension, pleural effusion and cerebral infarction, etc.. With the diagnostic results of DSA as the golden standard, the diagnostic sensitivities of MSCT, MRI and MSCT combined with MRI were 92.94%, 87.82% and 98.71%, respectively (P<0.05). Conclusion MSCT combined with MRI is significantly better than single MSCT or MRT in the diagnosis of pulmonary embolism. It can be used as a reference for the diagnosis of pulmonary embolism.

【关键词】多层螺旋CT;磁共振成像;肺动脉栓塞;数字减影血管造影

【中图分类号】R563.5

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.09.007

前言

肺动脉栓塞是由于外源性或内源性栓子阻塞肺动脉引起肺循环障 碍的综合征,近年来,随着饮食结构的变化及人口老龄化进程的加 快,肺动脉栓塞的发病率逐年上升[1]。肺栓塞死亡率较高,如能及时 诊断并采用溶栓及抗凝治疗,死亡率可显著下降,但肺动脉栓塞临床 表现及疾病进展程度差异较大,缺乏固定的临床特征,为及时诊断带 来困难[2-3]。影像学检查是肺动脉栓塞的重要诊断手段之一,多层螺旋 CT在肺动脉造影方面扫描速度较快,可清晰显示中心肺动脉栓塞,对 较细的肺动脉栓塞也有较大的诊断价值[4]。近年来,磁共振成像(MRI) 也被逐渐用于肺动脉栓塞的诊断中,取得一定的临床诊断效果[5]。本 研究将多层螺旋CT与MRI结合起来进行肺动脉栓塞的诊断,取得较好的 效果,现报道如下。