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多层螺旋CT胸部健康体检中源图像对肺部以外病变的诊断价值

作者:赵厚亮 徐 凯

所属单位:徐州医科大学附属医院影像科(江苏 徐州 221000)

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摘要

目的评价多层螺旋CT胸部健康 体检图像对肺部以外病变的诊断价值。方 法 回顾性分析1866例徐州医科大学及徐 州医科大学附属医院在职及离退休职工胸 部健康体检人员,由两名放射科医师按 肺部以外病变所发生的部位对病变进行 统计。对肺部以外病变的行临床意义评 分:1分:没有临床意义,即不需要进一 步检查或随访的病变;2分:需要临床重 视,即需要进一步检查明确诊断或随访 的病变;3分:可能危及患者生命,即需 临床采取积极有效治理措施的病变。不 相关的病变(如颈椎、胸椎退行性改变) 未纳入统计。1分被认为无临床意义组, 2分、3分被认为有临床意义组。结果 在 1856例体检人员中,发现660例(33.6%)有 941个肺部以外病变。17.9%(118/660)患 者有多部位病变,其中5.8%(55/941)发生 于乳腺,41.6%(391/941)发生于纵隔, 2.0%(19/941)发生于骨,6.6%(62/941) 发生于甲状腺,44.0%(414/941)是腹 部。在腹部病变中,肝囊肿、肝内钙 化灶、脂肪肝、胆囊结石、肾上腺结 节发生率分别为47.3%(196/414)、 25.6%(106/414)、19.1%(79/414)、 6.3%(26/414)、2.2%(9/414)。临床意义 评价结果,1、2、3分病变的发生率分 别为8.5%(36/941)、81.15(344/941)和 10.4%(44/941)。结论 多层螺旋CT胸部健 康体检中图像具有重要的临床诊断价值, 可提示对临床有重要价值的肺部以外病 变。观察源图像时调节不同窗宽窗位对肺 部以外病变的检出具有重要意义。

Objective To assess the clinical value of multi-detector computed tomography(MDCT) source image on detecting extrapulmonary abnormalities in a large cohort of physical examination patients. Methods MDCT source images from 1866 consecutive physical examination patients(mean 51.2 years) were reviewed retrospectively by 2 readers. Extra-pulmonary findings were classified according to involved organ and level of clinical significance. Clinical relevance of extracoronary findings was considered as either "non-significant" or "significant". "Non-significant" findings were subclassified as score 1: findings without clinical implication findings necessitating immediate therapeutic actions. "Significant" findings were assigned to score 2: findings with uncertain clinical or prognostic relevance, requiring clinical awareness, follow-up or further investigations(non-urgent), or score 3: findings necessitating immediate therapeutic actions. The irrelevant incidental findings (C-spinal or T-spinal degenerative changes) were not analyzed. Results Extrapulmonary findings was evidenced in 660 patients with 941 abnormalities. 17.9%(118/660) patients had multiple lesions, 5.8%(55/941) lesions were located in the breast, 44.0%(414/941)lesions found in the upper abdomen, 41.6%(391/941)lesions evidenced in the mediastinum, 2.0%(19/941)lesions seen in the spine, 6.6%(62/941)lesions located in the thyroid. The clinical significance score 1-3 was 8.5%(36/941), 81.1%(344/941) and 10.4%(44/941) respectively. Conclusion Our data show that there is clinical value to observe and report extrapulmonary findings with source image of pulmonary MDCT.

【关键词】低剂量螺旋CT;肺部;体检

【中图分类号】R322.3+5

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.09.002

前言

近年来,随着医疗技术的不断发展,低剂量多层螺旋 CT(multidetector computed tomography,MDCT)已经越来越多的运用 到了肺癌的筛查中,因其放射计量低,可发现很小的结节病变,对早 期的肺癌诊断具有较高的敏感性[1-4]。在进行肺部MDCT检查时,在有限 的视野范围(FOV)内除了包含了双肺,也包含了甲状腺、纵膈、食管、 骨及部分上腹部等结构,因此源图像中偶尔会发现肿瘤等其他肺部以 外的疾病。目前关于胸部健康体检的研究局限于双肺的病变,对源图 像诊断肺部以外病变的报道少见。本文旨在阐述在肺部MDCT检查时, 源图像对于诊断甲状腺结节、肝脏病变、乳腺癌等其他肺部以外疾病 的价值。