目的探究应用3.0T动态增强 磁共振功能成像(DCE-MRI)及4D-Tissue 软件定量判定宫颈癌的诊断价值。方 法 选取2013年1月-2015年3月行DCE-MRI 扫描的30例宫颈癌患者。所有的病例均 经过病理证实。患者年龄33-67岁[平均 (48±10)岁]。患者治疗前行DCE-MRI检 查及定量分析，比较肿瘤组织与子宫肌 层的TIC曲线特征，采用独立样本t检验 比较肿瘤组与肌层对照组各定量参数的 差异。结果 宫颈癌组织与子宫肌层TIC 曲线：肿瘤以III型曲线为主，III型26 例(86.67%)；子宫肌层以I型曲线为主， I型18例(60%)。肿瘤组织与子宫肌层各 定量参数值之间进行比较：肿瘤组与子 宫肌层组的Ktrans、Ve、Kep值差异有统计学 意义(P<0.05)。肿瘤组平均Ktrans值、平 均Ve值、平均Kep值明显高于正常子宫肌层 组。结论 DCE-MRI各定量参数对诊断宫颈 癌病变拥有一定效用。

Objective To explore the diagnostic value of cervical carcinoma through the quantitative analysis of 3.0T dynamic enhanced MRI (DCE-MRI) and 4D-tissue technology. Methods 30 cases of cervical carcinoma from January 2013 to March 2015 were included in our study. All the cases had been confirmed by pathology. Patients aged 32-66 [An average of (47±10)]. Before treatment, all the patients were scanned by DCE-MRI. We compared TIC curve characteristics of tumor tissue and myometrium, used independent sample t test to compare the quantitative parameters of cervical cancer group and normal myometrium group. Results Tumor tissue and uterine muscle TIC curve: The tumors were given priority to type III curve, 26 cases of type III(86.67%). The uterine muscles were given priority to type I curve, 18 cases of type I (60%). The value of Ktrans, Ve and Kep between tumors and uterine muscles group had statistically significant difference(P<0.05). The average value of Ktrans, Ve and Kep for tumor tissues were significantly higher than normal uterine muscles group. Conclusion The quantitative parameters of DCE-MRI have a certain efficiency in the diagnosis of cervical carcinoma.