论著-头颈部
CTA诊断冠状动脉狭窄的临床价值
作者:闫振富1 陈 晖1 荆宏峰2
所属单位:1.郑州大学附属郑州中心医院老年心内科 2.郑州大学附属郑州中心医院放射科(河南 郑州 450000)
PDF摘要
目的探讨电子计算机断层 扫描血管造影(Computed Tomography Angiography,CTA)诊断冠状动脉狭窄的 临床价值。方法 随机选取我院2016年10 月-2017年10月收治的82例疑似冠心病患 者作为研究对象,对其行CTA检查与数 字减影血管造影(Digital Subtraction Angiography,DSA),将DSA检查结果 作为金标准进行比较。结果 DSA检查 出79例阳性与3例阴性,CTA检查出75 例冠状动脉阳性与7例阴性,灵敏度为 96.10%(74/77),特异度80.00%(4/5),准 确性95.12%(78/82),Kappa值为0.64; CTA与DSA对冠状动脉狭窄程度的检查结 果比较无统计学意义(P>0.05);CTA 检查左主干灵敏度为95.24%(40/42), 特异度100.00%(40/40),准确性 97.56%(80/82),Kappa值为0.95; 左前降支灵敏度为95.00%(57/60), 特异度100.00%(22/22),准确性 96.34%(79/82),Kappa值为0.91; 左回旋支灵敏度为92.16%(47/51), 特异度96.77%(30/31),准确性 93.90%(77/82),Kappa值为0.87;右 冠状动脉灵敏度为95.24%(40/42), 特异度100.00%(40/40),准确性 97.56%(80/82),Kappa值为0.95。结论 CTA能够清楚显示患者冠脉病变情况,准 确性高,敏感性及特异性良好,能够辅助 诊断并且筛查冠状动脉狭窄。
Objective To explore the clinical value of computed tomography angiography (CTA) in the diagnosis of coronary artery stenosis. Methods A total of 82 patients with suspected coronary heart disease who were admitted to the hospital from October 2016 to October 2017 were randomly selected as the subjects. They were examined by CTA and digital subtraction angiography (DSA), and the results were compared with results of DSA as the golden standard. Results There were 79 cases positive and 3 cases negative detected by DSA, while there were 75 cases of coronary arteries positive and 7 cases negative detected by CTA. The sensitivity, specificity, accuracy and Kappa value were 96.10% (74/77), 80.00% (4/5), 95.12% (78/82) and 0.64, respectively, without significant difference between CTA and DSA in detecting the degree of coronary artery stenosis (P>0.05). The sensitivity, specificity, accuracy and Kappa value of CTA for left main stem were 95.24% (40/42), 100.00% (40/40), 97.56% (80/82) and 0.95, respectively, those for left anterior descending branch were 95.00% (57/60), 100.00% (22/22), 96.34% (79/82) and 0.91, for left circumflex branch were 92.16% (47/51), 96.77% (30/31), 93.90% (77/82) and 0.87, and for right coronary artery were 95.24% (40/42), 100.00% (40/40), 97.56% (80/82) and 0.95, respectively. Conclusion CTA can clearly display coronary artery lesions, with high accuracy, sensitivity and specificity. It can help diagnosis and screening of coronary artery stenosis.
【关键词】电子计算机断层扫描血管造影;冠状动脉狭窄;选择性冠脉造影术;诊断价值
【中图分类号】R814.42;R543.3
【文献标识码】A
【DOI】10.3969/j.issn.1672-5131.2018.07.009
前言
在人们生活水平不断提升的条件下,心血管疾病临床发病率越来 越高,用于诊断冠心病的方式亦逐渐增多。冠心病可对人类健康造成 严重威胁,且致死率高,故及时准确筛查该病具有非常重要的意义。 数字减影血管造影(Digital Subtraction Angiography,DSA)是临床 诊断冠脉狭窄病变金标准,其对冠心病患者冠脉狭窄病变检测阳性率 超过60.0%[1-2]。然而,DSA属于有创检查,操作中可能损伤患者血管内 膜,并发症风险高。多排螺旋电子计算机断层扫描血管造影(Computed Tomography Angiography,CTA)技术由于其便捷、无创以及有效等特 点受到了临床诊断的青睐,不仅可提高患者依从性,且其成像空间与 密度也很高,进一步扩大了临床应用范围[3-4]。本文以82例疑似冠心病 患者作为研究对象,探讨CTA诊断冠状动脉狭窄的临床价值。现汇报如 下。
中国CT和MRI杂志
第16卷, 第 7 期
2018年07月
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