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肝细胞癌患者超声及CT征象特点分析

作者:李东风1 杜红升2 马 静1 王 晶1

所属单位:1.洛阳市第三人民医院超声科(河南 洛阳 471002) 2.洛阳市第三人民医院影像科(河南 洛阳 471002)

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摘要

目的探讨肝细胞癌患者超声及 CT征象特点。方法 回顾性分析2012年2 月-2017年2月本院收治的126例肝细胞癌 患者临床资料,依据患者行超声检查(记 为超声组,n=65)及CT检查(记为CT组, n=61)分为两组,比较两组影像学征象特 点,并分析超声及CT诊断肝细胞癌的效 能。结果 CT诊断肝细胞癌的灵敏度、 特异度和准确度各为80.39%、80.00%、 80.33%与超声诊断肝细胞癌的灵敏度、 特异度和准确度各为77.36%、83.33%、 78.46%相较无显著差异(P>0.05);增强 CT常表现为“快进快出”强化特征,动 脉期病灶出现不同程度强化、高或等密 度,门脉期强化减弱、呈稍高、等或低 密度,平衡期强化减弱为低密度;超声 检查以快进快出增强模式为主要表现, 动脉期病灶呈高增强信号,门脉其消退 呈低增强,延迟期病灶基本廓清。结论 肝细胞癌患者超声及CT影像学征象各具 特点,两者在肝细胞癌良恶性鉴别诊断 中的效能相当,在肝细胞癌良恶性鉴别 诊断中有一定应用价值。

Objective To investigate the ultrasound and CT features of patients with hepatocellular carcinoma (HCC). Methods The clinical data of 126 patients with HCC admitted to the hospital from February 2012 to February 2017 were retrospectively analyzed. The patients were examined by ultrasound (ultrasound group, n=65) and CT (CT group, n=61). The imaging signs were compared between the two groups, and the efficiencies of ultrasound and CT in the diagnosis of HCC were analyzed. Results The sensitivity, specificity and accuracy of CT in the diagnosis of HCC were 80.39%, 80.00% and 80.33% respectively, while those of ultrasound were 77.36%, 83.33% and 78.46% respectively (P>0.05). Contrast-enhanced CT showed fast in and fast out enhancement characteristics. Lesions showed different degrees of enhancement, high or equal density in arterial phase, weakened enhancement, slightly higher, equal or low density in portal phase, weakened enhancement and low density in balance phase. The main manifestation of ultrasound examination was fast in and fast out enhancement pattern. Lesions showed highly enhanced signals in arterial phase, low enhancement in portal phase and lesions basically cleared in the delayed phase. Conclusion The ultrasound and CT images of patients with HCC are characteristic. The efficiencies of the two are similar in the differential diagnosis of benign and malignant HCC. They are of certain application value in differential diagnosis of benign and malignant HCC.

【关键词】肝细胞癌;超声;CT;效能

【中图分类号】R735.7

【文献标识码】A

【DOI】10.3969/j.issn.1672-5131.2018.07.028

前言

肝细胞癌为临床常见恶性肿瘤,具有病情进展迅速、预后差、发 病率及病死率高等特点,多继发于肝炎肝硬化,对患者生命健康造成 严重影响,尽早发现和合理诊治对改善患者预后尤为重要[1]。现阶段 临床对肝癌的诊断主要依赖于影像学检查,早期常采用超声影像学对 肝细胞癌进行鉴别诊断,其主要通过对癌灶尺寸、位置、数量、形态 等的显示,在肝脏局限性病变定性诊断中发挥重要作用,但其易受气 体、肥胖以及角度等的影响,因而临床推广应用存在一定局限性[2-3] ; 随着影像学技术不断进展,CT在肝细胞癌患者鉴别诊断中起到重要 作用,尤其是增强CT被国外学者认为是肝细胞癌首选无创性检查手 段[4]。但一直以来临床对超声及CT诊断肝细胞癌的效能差异尚缺乏统 一定论,为此笔者于本文展开临床回顾性分析,结果报告如下。