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多层螺旋CT平扫及三期动态增强扫描对肝细胞癌的诊断价值研究*

作者:张海涛

所属单位:陕西省汉中市人民医院放射科(陕西 汉中 723000)

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摘要

目的探讨分析多层螺旋 CT(MSCT)平扫及三期动态增强扫描对肝细 胞癌诊断中的应用价值。方法 回顾性分 析2015年3月到2017年3月期间收集的52例 经手术病理证实患有肝细胞癌患者的CT检 查资料,分析CT平扫及三期增强扫描对肝 细胞癌的诊断应用价值。结果 ①运用64 排128层螺旋CT多期增强扫描共诊断出14 例患者伴有肝硬化,共检出肝癌病灶82 个,病灶在CT平扫上显示为稍低密度,在 三期动态增强扫描中病灶为“快进快出” 式典型强化,具体表现为动脉期强化,其 中3个病灶动脉期未明显强化;门脉期强 化程度逐渐下降,延迟期呈低密度。与手 术病理诊断结果相比,64排128层螺旋CT 多期增强扫描三期综合检出率高达100%。 ②多层螺旋CT三期动态增强扫描对肝细胞 癌的病灶检出率分别为:动脉期检出率达 为96.34%,门脉期的检出率为82.92% , 延迟期的检出率为87.80%。结论 在临床 肝细胞癌诊断中,运用64排128层螺旋CT 多期增强扫描,可以清晰反映肝细胞癌的 血供变化特点,为临床早期诊断肝细胞癌 提供可靠的影像学依据,在肝细胞癌诊断 以及病情监测方面有重要的临床意义。

Objective To investigate the value of multi-slice spiral CT (MSCT) plain scanning and three-phase dynamic contrast-enhanced scanning in the diagnosis of hepatocellular carcinoma. Methods CT findings of 52 patients with hepatocellular carcinoma confirmed by surgery and pathology collected from March 2015 to March 2017 were analyzed retrospectively. The CT and CT scanning were analyzed retrospectively. Results ①There was a total of 82 liver cancer lesions detected in 14 patients with cirrhosis by using 128-slice spiral CT multi-phase contrast-enhanced scan. The lesion displayed a slightly lower density on plain scan, scan lesions in the "fast forward fast" typical enhancement, manifested as arterial phase enhancement, 3 lesions were not significantly enhanced arterial phase; portal phase gradually decreased, the delay period showed low density. Compared with the results of surgical pathology, the comprehensive detection rate of three stages of 64-slice 128-slice spiral CT multi-phase enhanced scan was as high as 100%. ②The detection rate of three-phase dynamic enhanced CT scan of hepatocellular carcinoma by multi-slice spiral CT were as follows: the detection rate of arterial phase was 96.34%, the detection rate of portal phase was 82.92%, the detection rate of delayed phase was 87.80%. Conclusion In the clinical diagnosis of hepatocellular carcinoma, 64 rows of 128-slice spiral CT multi-phase enhanced scan can clearly reflect the characteristics of blood supply of hepatocellular carcinoma and provide a reliable imaging basis for the early diagnosis of hepatocellular carcinoma. Hepatocellular carcinoma diagnosis and disease monitoring has important clinical significance.

【关键词】多层螺旋CT;平扫;增强扫描;肝细胞癌;诊断应用

【中图分类号】R735.7

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.07.026

前言

肝是人体重要的解毒器官,肝癌会对人们的生活健康和品质造成 严重威胁。按照形态学划分,肝癌可分为巨块型、结节型和弥漫型。 最常见的是巨块型,癌组织比较容易发生坏死,甚至可引起肝脏损 坏。而最少见的就是弥漫型,往往会出现肝功能衰竭现象[1]。肝细胞 癌是一种死亡率高的原发性肝癌,早期症状不明显,到了晚期,会出 现肝痛、无力、人会日益消瘦、腹水等症状[2]。随着医学影像学的发 展,肝细胞癌的诊断方法有很多种,包括B超检查、CT检查、MRI检查 等检查手段[3]。而CT增强扫描与MRI检查是目前来说诊断肝细胞癌中最 常用的影像学检查方法。随着影像学技术的不断发展,CT增强扫描技 术越来越成熟,也因为其分辨率高等优点在肝细胞癌的早期确诊率越 来越高[4]。本文回顾性分析我院2015年3月到2017年3月收集的52例经 手术病理证实患有肝细胞癌患者的CT检查资料,分析CT平扫和动态增 强扫描在肝细胞癌诊断中的应用价值。