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论著-头颈部

不同影像学方法在 诊断脊柱结核中的 应用

作者:石广灿

所属单位:新乡医学院第一附属医院结核内科 (河南 新乡 453000)

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摘要

目的 探究不同影像学方法在诊 断脊柱结核中的应用价值。方法 回顾性 分析2014年6月-2017年6月间收治的75例 脊柱结核患者临床资料,所有患者均行 磁共振成像(MRI)、电子计算机断层扫描 (CT)检查。比较2种影像学检查图像质 量及结核阳性征象检出率(椎旁脓肿、 椎管狭窄、钙化情况、骨质坏死)。结 果 ①MRI和CT图像质量良好率对比差异 无统计学意义(P>0.05);②MRI和CT比 较,骨质破坏检出率差异均无统计学意义 (P>0.05),MRI较CT椎旁脓肿、椎管狭窄 检出率高(P<0.05),而CT较MRI骨质坏死 检出率高(P<0.05);③CT显示多数患者存 在不同程度的椎体骨质破坏,可表现为洞 穴状、虫蚀样、碎裂型改变,钙化为砂砾 状、斑点状或环状等;MRI中T1多数呈现 低信号,少数呈现等、低混杂信号;T2 多呈现均匀高信号或混杂信号。结论 CT 和MRI均是有效诊断脊柱结核的影像学检 查,但MRI在椎旁脓肿及椎管狭窄检出中 更有优势,CT在检出死骨中更有优势。

Objective To explore the application values of different imaging methods in the diagnosis of spinal tuberculosis. Methods The clinical data of 75 cases of patients with spinal tuberculosis treated in our hospital from June 2014 to June 2017 were retrospectively analyzed. All patients were given magnetic resonance imaging (MRL) and computerized tomography (CT). The image quality and detection rate of tuberculosis positive signs (bone destruction, paravertebral abscess, spinal canal stenosis, calcification, osteonecrosis) were compared between the 2 imaging methods. Results ①There was no difference in the image quality of MRI or of CT (P>0.05). ② There was no significant difference in the detection rate of bone destruction between MRI and CT (P>0.05), and the detection rates of paravertebral abscess and calcification were higher in the MRI compared with those in the CT (P<0.05) while the detection rate of osteonecrosis was lower (P<0.05). ③CT showed that most patients were with varying degrees of vertebral bone destruction, which could be characterized by cave-like, worm-eaten, fragmented changes. Calcification was with gravel, speckled or ring shape. In MRI, most of the T1 showed low signal, and a few presented equal and low hybrid signals, and T2 mostly showed uniform high signal or mixed signal. Conclusion Both CT and MRI are effective imaging methods for the diagnosis of spinal tuberculosis, but MRI is more advantageous in the detection of paraspinal abscesses and spinal stenosis, and CT is more advantageous in the detection of dead bone.

【关键词】磁共振成像;电子计算机断层 扫描;脊柱结核;诊断价值

【中图分类号】R529.2;R445.2;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.06.040

前言

随着结核杆菌耐药性增强及免疫性疾病的增长,近年来结核感染 率呈回升趋势。脊柱结核起病缓慢,早期症状多不明显,但随着病情 迁延可造成椎体畸形和截瘫,临床后果严重,且因缺乏特异性病理表 现,早期确诊难度较大[1]。相关研究表明临床脊柱结核早期诊断不容 乐观,脊柱结核的初诊误诊率可达78.26%[2]。影像学检查有利于发现 患者脊椎基本病变,对脊柱结核诊治具有重要意义,目前磁共振成像 (MRI)和电子计算机断层扫描(CT)在临床运用较多[3]。国内外均有相 关研究探讨CT与MRI在脊柱结核中的诊断作用,但对CT与MRI的价值优 劣仍存在争议。基于此,本研究回顾性分析我院收治75例脊柱结核患 者临床资料,以探究不同影像学方法在诊断脊柱结核中的应用价值。