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DSCTA冠状动脉血管 成像对于冠心病患 者PCI支架内再狭窄 诊断的价值分析

作者:丁学智1 杨 鉴2 胡示超2

所属单位:1.河南省鹤壁市人民医院心内科 (河南 鹤壁 458030) 2.河南省鹤壁市人民医院放射科 (河南 鹤壁 458030)

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摘要

目的 分析双源CT(DSCTA)冠状动 脉血管成像对于冠心病患者PCI支架内再 狭窄(ISR)诊断的价值。方法 回顾性分析 2013年7月-2015年3月于我院行PCI患者的 临床资料,筛选67例行DSCTA及冠脉造影 患者作为本次研究对象,以冠脉节段为单 位对比两种检查方式的影像质量,并明确 DSCTA的诊断价值。结果 67例患者共70个 支架,共扫描268个节段,以冠脉节段为 单位,DSCTA的图像质量等级分布与冠脉 造影比较无差异(P﹥0.05);截止终访,15 例患者经冠脉造影明确为ISR,DSCTA诊断 ISR的灵敏度为94.11%、特异度92.45%、 准确率92.85%、阳性预测值80.00%、阴 性预测值98.00%,Kappa值0.816。结论 DSCTA诊断ISR具良好的诊断效能,与冠脉 造影检查结果一致性良好,且安全性。

Objective To analyze the value of dual source CT (DSCTA) coronary angiography in the diagnosis of PCI in-stent restenosis (ISR) in patients with coronary heart disease (CHD). Methods The clinical data of patients undergoing PCI in the hospital from July 2013 to March 2015 were retrospectively analyzed. 67 patients undergoing DSCTA and coronary angiography were selected as the subjects. The image quality of two examination methods was compared with coronary artery segment as unit, and the diagnostic value of DSCTA was identified. Results There were 70 stents in 67 patients, and 268 segments were scanned. There was no difference in image quality rank distribution between DSCTA and coronary angiography with coronary artery segment as unit (P>0.05). At the end of follow-up, 15 patients were diagnosed as ISR by coronary angiography. The sensitivity, specificity, accuracy rate, positive predictive value, negative predictive value and Kappa value of DSCTA in the diagnosis of ISR were 94.11%, 92.45%, 92.85%, 80.00%, 98.00% and 0.816, respectively. Conclusion The diagnostic efficiency of DSCTA for ISR is good and the consistency with results of coronary angiography is good, with safety.

【关键词】DSCT;冠状动脉血管成像;冠 心病;PCI支架内再狭窄

【中图分类号】R541.4;R445.3

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.06.004

前言

支架内再狭窄(ISR)是冠心病患者冠状动脉支架置入术(PCI)后易 发生的常见并发症之一,也是导致冠心病患者再次行靶血管血运重建 的重要原因。随着药物涂层支架的出现,ISR虽有所减少,当仍未能有 效避免,并已成为冠心病患者PCI术后心肌缺血、心肌梗死的重要危险 因素[1]。当前评价ISR的主要手段为冠脉造影,但作为有创性检查,用 于ISR易并发极严重并发症反应。而双源CT冠脉血管成像(DSCTA)不仅 无创,且在时间及密度分辨率上均有显著优势,研究认为,DSCTA不仅 能对冠脉狭窄程度进行显示,还能反应血管腔内构造,且具优势高心 率容忍度[2]。为进一步明确DSCTA的临床优势,先以冠脉造影为评估标 准,对DSCTA评估ISR的诊断效能进行评价,具体报道如下。