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炎症性肠病多层螺 旋CT小肠增强造影 影像学特点及与常 规结肠镜检查结果 对比分析*
作者:杨文义1 李德亮2 王大勇3
所属单位:1.河南大学第一附属医院消化内科 (河南 开封 475000) 2.郑州大学第一附属医院消化内科 (河南 郑州 475000) 3.河南大学第一附属医院CT室 (河南 开封 475000)
PDF摘要
目的 分析炎症性肠病多层螺旋 CT小肠增强造影影像学特点及与常规结 肠镜检查结果对比。方法 本研究观察对 象选择我院经病理诊断确诊的138例IBD患 者,其中克罗恩病98例,溃疡性结肠炎 40例,回顾性分析所有患者MSCTE影像学 以及结肠镜检查资料,分析MSCTE影像学 特点并与结肠镜检查结果进行比较。结 果 CD患者MSCTE检查肠腔狭窄、多节段性 病变、肠周脂肪间隙模糊、肠系膜血管增 生以及瘘管形成或腹腔脓肿人数比例显著 高于UC患者,结肠带消失显著低于UC患 者,差异具有统计学意义(P<0.05),肠壁 强化、肠壁增厚、肠周淋巴结增多差异无 统计学意义(P>0.05);MSCTE能诊断IBD结 肠带消失等肠外病变、肠壁增厚以及肠壁 强化,结肠镜无法诊断,差异具有统计学 意义(P<0.05),结肠镜能诊断IBD卵石征 与肠壁溃疡,MSCTE不能,差异具有统计 学意义(P<0.05),MSCTE诊断多节段病变 敏感性显著高于结肠镜,多发炎性息肉敏 感性显著低于结肠镜,差异具有统计学意 义(P<0.05),肠腔狭窄均有较高的诊断效 能,诊断敏感性、特异度差异无统计学 意义(P>0.05)。结论 MSCTE能更好诊断 IBD,优势在于肠外病变、肠壁增厚以及 肠壁强化,以及对多节段病变诊断敏感性 较高,结肠镜能更好诊断卵石征、肠壁溃 疡以及多发炎性息肉。
Objective To investigate imaging features of multi—slice computer tomography enterography(MSCTE) in the diagnosis of inflammatory bowel disease (IBD), and to compare with the results of the conventional colonoscopy. Methods In this study, 138 IBD patients diagnosed by pathology in our hospital were selected, among them, 98 cases were Crohn's disease (CD), and 40 cases were ulcerative colitis (UC). The MSCTE and colonoscopy imaging data of all patients were retrospectively analyzed. The features of MSCTE were analyzed and compared with those of colonoscopy. Results The MSCTE imaging showed that the incidence rate of stenosis of enteric cavity, multi-segmental lesions, density increase of mesentery, proliferation of mesenteric vascular bundle, fistula formation, sinus in CD patients were higher than those in the UC patients, while the proportion of disappearance of the colonic bands among CD patients was lower than that in the UC patients (P<0.05), no difference was found in the incidence rate of the enhancement of intestinal wall, thickeness of intestinal wall and increasing peri enteric lymph node between groups (P>0.05). MSCTE could diagnose parenchymal lesions such as disappearance of IBD colon band, thickening of bowel wall and enhancement of bowel wall, which could not be diagnosed by colonoscopy, the difference was statistically significant (P<0.05). Colonoscopy could diagnosed IBD sclera and intestinal wall ulcer, which could not be diagnosed by MSCTE, the difference was statistically significant (P<0.05). The sensitivity of MSCTE for diagnosing multisegmental lesions was significantly higher than that of colonoscopy, while colonoscopy had a higher sensitivity in diagnosing multiple polyps, the difference was statistically significant (P<0.05). The sensitivity and specificity of the diagnosis of intestinal stricture was not statistically significant (P>0.05). Conclusion MSCTE has advantages in demonstrating intestinal wall thickening, enhancement of intestinal wall and extraintestinal complications of IBD, while colonoscopy is easy to demonstrate the IBD sclera and intestinal wall ulcer.
【关键词】炎症性肠病;MSCTE;结肠镜
【中图分类号】R322.4+5
【文献标识码】A
【DOI】10.3969/j.issn.1672- 5131.2018.06.034
前言
IBD为累及直肠、回肠以及结肠的特发性肠道炎症疾病,也是临床 上常见的消化道疾病。以腹泻及腹痛为主要临床表现,严重者可有血 便出现。IBD主要包括UC与CD两种,以CD比例较高。UC是结肠黏膜层出 现的连续性炎症,最先受累部位为直肠,逐渐蔓延至全结肠[1]。CD可 至全消化道受累,属于非连续性炎症,回肠末端、结肠以及肛周是主 要受累部位。受到遗传、环境、感染以及免疫因素的影响,IBD发病率 具有逐年上升趋势[2]。IBD的治疗方案确定以及预后效果与早期全面评 价以及正确诊断具有十分重要的关系。结肠镜检查是既往IBD诊断的常 规方法,但其几乎无肠外病变的诊断能力,因此对IBD病情的全面评估 具有一定的局限[3]。近年随着影像学技术的进步,MSCTE在IBD的诊断 方面表现出一定优势,Zakeri N等[4]认为MSCTE既能有效评估肠管及肠 壁的变化,对肠外病变的诊断也较为准确。现为进一步探究MSCTE在 IBD的诊断价值,分析IBD MSCTE影像学特点及与常规结肠镜检查结果 对比,报道如下。
中国CT和MRI杂志
第16卷, 第 6 期
2018年06月
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