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磁共振成像在子宫 内膜癌术前诊断中 的价值

作者:陈粉合1 邓 祎2 杨海霞1 王 宇3

所属单位:1.河南省郑州市第七人民医院妇科 (河南 郑州 450000) 2.河南省郑州市第七人民医院急诊 科 (河南 郑州 450000) 3.河南省郑州市第七人民医院影像 科 (河南 郑州 450000)

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摘要

目的 探讨磁共振成像(MRI)在 子宫内膜癌术前诊断中的价值。方法 选 取2015年1月至2017年9月在我院治疗的 124例子宫内膜癌患者,比较术前MRI检 查结果与病理结果。结果 术前MRI临床 分期与病理分期结果一致性Kappa值为 0.724,P<0.05,一致性较好;术前MRI 评价肌层浸润与术后病理结果一致性 Kappa值为0.741,P<0.05,一致性较 好;术前MRI评价浅肌层浸润灵敏度、 特异度、阳性预测值、阴性预测值和准 确度分别为86.44%、87.69%、86.44%、 87.69%和87.10%;术前MRI评价盆腹腔淋 巴结转移与术后病理结果一致性Kappa值 为0.275,P<0.05,一致性较差,术前 MRI评价盆腹腔淋巴结转移的灵敏度、特 异度、阳性预测值、阴性预测值和准确度 分别为22.22%、98.26%、50.00%、94.17% 和92.74%。结论 MRI术前诊断子宫内膜癌 临床分期、判断肌层浸润情况有较好的应 用价值,但判断盆腹腔淋巴结转移的应用 价值不高。

Objective To explore the value of magnetic resonance imaging (MRI) in the diagnosis of endometrial carcinoma before operation. Methods 124 cases of endometrial cancer were treated in our hospital from January 2015 to September 2017, and the results of preoperative MRI examination and postoperative pathological results were compared. Results The Kappa value of preoperative MRI clinical staging and postoperative pathological staging was 0.724, P<0.05, and the consistency was better. Preoperative MRI evaluation of myometrium infiltration and postoperative pathological results showed that the Kappa value was 0.741, P<0.05, and the consistency was better. Preoperative MRI evaluation of superficial muscle layer invasion showed that the sensitivity, specificity, positive predictive value, negative predictive value and accuracy were 86.44%, 87.69%, 86.44%, 87.69% and 87.10%, respectively. Preoperative MRI evaluation of pelvic and abdominal lymph node metastasis and postoperative pathological results showed that Kappa value was 0.275, P<0.05, the consistency was poor,the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of preoperative MRI for pelvic and abdominal lymph node metastasis were 22.22%, 98.26%, 50%, 94.17% and 92.74%, respectively. Conclusion MRI preoperative diagnosis of endometrial carcinoma clinical staging and evaluation of myometrium infiltration has good application value, However, it has low application value to judge pelvic and abdominal lymph node metastasis.

【关键词】磁共振成像;子宫内膜癌;临 床分期;肌层浸润

【中图分类号】R711.32

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.06.033

前言

子宫内膜癌指原发于子宫内膜的上皮性的恶性肿瘤,多好发于绝 经女性。个体差异、临床分期、癌细胞的分化程度等均是影响子宫 内膜癌治疗的重要因素,故而,本病的术前分期的准确判断较为重 要[1]。不同的影像学技术已被广泛应用于子宫内膜癌的诊断中,超声 和CT是子宫内膜癌常用诊断方法,但最新的研究[2]提示超声和CT期子 宫内膜癌的诊断敏感性较低;此外对晚期原发性子宫内膜癌转移灶 与原发灶的鉴别的特异性也较低。磁共振成像(magnetic resonance imaging,MRI)具有良好的组织对比度,组织分辨率高,可显著提高 肿瘤的预测范围,但目前关于子宫内膜癌的术前诊断资料较少[3]。故 此,本研究深入探讨了MRI在子宫内膜癌术前诊断中的价值,具体结果 进行如下汇报。