摘要
目的 探讨磁共振扩散加权成像 (DWI)、MR动态增强扫描诊断宫颈癌的临 床价值。方法 选取我院90例确诊宫颈癌 患者(宫颈癌组)、30例健康自愿者(对 照组),收集时间2016年3月至2017年10 月,对比两组的DWI b=800s/mm2 时的表观 扩散系数(ADC)值、MR动态增强扫描参数 (Ktrans:转运系数;Kep:速率常数;Ve: 容积分数);并根据病理学结果计算两种 方法单独及联合应用时诊断宫颈癌的临床 价值。结果 宫颈癌组的Ktrans、Kep值均显 著的高于对照组(P<0.05);宫颈癌组的 ADC值均显著的低于对照组(P<0.05);宫 颈癌和对照组的Ve值比较,差异无统计学 意义(P>0.05);DWI诊断宫颈癌的灵敏度 为85.56%、特异度为80.00%;MR动态增强 扫描诊断宫颈癌的灵敏度为87.78%、特异 度为86.67%;MR动态增强扫描联合DWI诊 断宫颈癌的灵敏度为95.56%、特异度为 93.33%。结论 DWI联合MR动态增强扫描诊 断宫颈癌能显著提高诊断的灵敏度和特异 度。
Objective To explore the clinical value of magnetic resonance diffusionweighted imaging (DWI) and MR dynamic enhanced scan in the diagnosis of cervical cancer. Methods In our hospital 90 cases of patients with cervical cancer (Cancer Group) and 30 healthy volunteers (control group), the collection time from March 2016 to October 2017, apparent diffusion coefficient between the two groups DWI b=800s/ mm2 table (ADC), the value of dynamic enhanced MR scanning parameters (Ktrans: Kep: transfer coefficient, rate constant, Ve: volume fraction); clinical value and pathological results according to the calculation of single and combined application of two methods in the diagnosis of cervical cancer. Results Cervical cancer group Ktrans, Kep values were significantly higher than the control group (P<0.05), cervical cancer group ADC values were significantly lower than the control group (P<0.05). Cervical cancer and control group Ve values, The sensitivity and specificity of DWI in diagnosing cervical cancer were 85.56% and 80.00% respectively. The sensitivity and specificity of MR dynamic contrastenhanced scan in diagnosing cervical cancer were 87.78% and 86.67% respectively. The MR dynamic contrast-enhanced The sensitivity of combined DWI in diagnosing cervical cancer was 95.56% and the specificity was 93.33%. Conclusion DWI combined with MR dynamic enhanced scanning of cervical cancer can significantly improve the diagnostic sensitivity and specificity.
【关键词】磁共振扩散加权成像;MR动态 增强扫描;诊断;宫颈癌
【中图分类号】R711.74
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.06.030
前言
宫颈癌是一类常见的妇科恶性肿瘤疾病,早期无明显症状,随着 病情发展常出现阴道流血、排液及尿频、尿急、便秘等症状,还可能 伴有肾盂积水及尿毒症等并发症[1]。宫颈癌常见类型包括鳞癌、腺癌 和腺鳞癌,其中腺癌中的黏液腺癌最为常见,可采用手术治疗(早期 宫患者)、放射治疗(中晚期患者)、化疗(晚期或复发转移患者)三种 方法按患者所处时期进行最佳处理[2-3]。为探讨磁共振扩散加权成像 (DWI)、MR动态增强扫描诊断宫颈癌的临床价值,本研究选取我院2016 年3月至2017年10月确诊的宫颈癌患者与健康自愿者进行对比分析,现 报告如下。
中国CT和MRI杂志
第16卷, 第 6 期
2018年06月
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