摘要
目的 探讨卵巢颗粒细胞瘤的MRI 特征表现,与术后病理结果对照。方法 回顾性分析40例外科切除后经病理证实的 成人型卵巢颗粒细胞瘤患者的临床及MRI 影像资料,评析MRI影像的特征表现及对 应之病理基础。结果 40例患者病灶均为 单发,MRI平扫的主要影像表现:子宫附 件区边界清楚、包膜完整的囊实性、囊性 或实性肿块。23例为多房蜂窝状囊实性肿 块,T1WI呈等低混杂信号,T2WI呈混杂高 信号,内有大小不等的囊变灶,囊内壁光 滑,无明确壁结节;11例为囊性肿块,单 房或多房性,直径多大于8cm,其囊内壁 均较光滑,囊内T1WI呈均匀一致低信号, T2WI呈一致高信号;6例为实性肿块,大 小约3-5cm,T1WI大致等同于同层肌肉信 号、T2WI高于同层肌肉信号。增强扫描40 例患者肿瘤实性部分及囊内分隔均明显强 化,囊内部分无强化表现;27例有腹水的 患者,其腹水含量与肿瘤大小无相关性 (r=0.19,P=0.08)。结论 成人型卵巢颗粒 细胞瘤在MRI影像表现上具有一定的特征 性,其特征影像表现为:①附件区呈蜂窝 状囊实性肿块,房间隔纤细,囊内壁光 滑,无壁结节最具有特征性;②囊性或实 性肿块边界清晰,肿瘤信号均匀一致,多 有假包膜。成人型卵巢颗粒细胞瘤的MRI 影像表现与病理表现基本吻合。
Objective To study the magnetic resonance imaging(MRI) features of adult ovarian granulose cell tumor and pathology correlation. Methods The clinical and MRI data of 40 patients with adult ovarian granulose cell tumor confirmed histologically were analyzed retrospectively. Results 40 cases showed single lesion which appeared as a cystic, solid or solid cystic mass with sharp margin within uterine attachment region on MRI plain scan. 23 cases had multilocular solid cystic masses, which showed low mixed signal areas in T1WI and high ones in T2WI, and had different sizes and a smooth inner wall without clear tubercles. 11 cases were a single loculus or multiple loculi cystic masses with 8cm or greater in diameter, within which smooth inner wall could be seen. MRI showed uniform low signal areas in T1WI and uniform high ones in T2WI. 6 cases were solid masses of about 3-5cm in size, which displayed a signal that equate to the same level muscle signal in T1WI and way above muscle signal in T2WI. On enhanced MRI scan, lesions of 40 cases demonstrated solidl enhancement or septal enhancement without cystic enhancement. Twenty-seven cases with ascites, there are no correlation about the Ascites levels to tumor size (r=0.19, P=0.08). Conclusion The typical MR imaging features were as follows: 1. loculi solid cystic mass within uterine attachment region with smooth inner wall and without clear tubercles. 2. Cystic or solid mass with sharp margin, uniform signal and pseudocapsule.MRI imaging of adult ovarian granulose cell tumor was consistent with pathologic assessment.
【关键词】卵巢;颗粒细胞瘤;磁共振成像
【中图分类号】R711.75
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.06.028
前言
卵巢颗粒细胞瘤(ovarian granulosa cell tumor,OGCT)是起源 于卵巢性索间质的低度恶性肿瘤,可分为成年型和幼年型,成年型多 见,主要发生在中年至绝经期后妇女,发病高峰年龄段为45~55岁, 成年型颗粒细胞瘤生长缓慢,预后好但易复发,手术为首选治疗方 式,需长期随访、动态监查[1]。本文对40例经手术病理证实的成人型 卵巢颗粒细胞瘤患者的MRI影像资料进行回顾性分析,探讨其MRI影像 表现特点,并与病理对照,旨在提高对此病诊断及鉴别诊断能力,为 临床诊治提供依据。
中国CT和MRI杂志
第16卷, 第 6 期
2018年06月
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