论著-头颈部
非增强CT值在预测 体外冲击波碎石术 治疗肾结石的应用 价值研究
作者:吕文选1 王丽琴1 胡云宇1 王峰岩1 张艾红2 巴 建2
所属单位:1.河南省职工医院泌尿外科 (河南 郑州 450000) 2.河南省职工医院放射科 (河南 郑州 450000)
PDF摘要
目的 探究非增强CT值在预测体 外冲击波碎石术(extracorporeal shock wave lithotripsy,ESWL)治疗肾结石的 应用价值研究,为体外冲击波碎石疗效预 测提供理论依据。方法 本研究纳入对象 为2016年4月-2017年4月于我院接受ESWL 治疗的120例肾结石患者,术前采用非增 强CT进行结石软组织窗CT值的测定,按CT 值≤500HU、500-1000HU、≥1000HU分为 低(49例)、中(36例)、高密度组(35例), 所有患者均采用ESWL治疗,比较三组患者 碎石效果,记录三组患者ESWL次数以及平 均冲击次数。结果 低密度组碎石无效、 碎片残留率最低,碎石有效率最高,三组 碎石无效、碎片残留率、碎石有效率差异 显著,组间两两比较差异具有统计学意义 (P<0.05),低密度组结石粉碎率最高,显 著高于中、高密度组,差异具有统计学意 义(P<0.05),中、高密度组结石粉碎率差 异无统计学意义(P>0.05);低密度组平均 冲击次数、ESWL次数、CT值最低,三组比 较差异显著,组间两两比较差异具有统计 学意义(P<0.05)。结论 不同非增强CT值 肾结石患者ESWL治疗效果差异显著,临床 可运用非增强CT值预测ESWL治疗效果,为 肾结石治疗方案的确定提供理论依据。
Objective To investigate the application value of non-contrast CT (NCCT) in the outcomes prediction of extracorporeal shock wave lithotripsy (ESWL) for renal stone, and to provide a theoretical basis for the curative effect prediction of ESWL. Methods In this study, 120 patients with renal stone underwent ESWL in our hospital from April 2016 to April 2017 were enrolled. The CT value ranges of the soft tissue window were determined by NCCT, patients were divided into three groups according to the CT values, namely low-density group (49 cases), middle-density group (36 cases), highdensity group (35 cases) with CT values ranging from ≤ 500 HU, 500 -1000 HU, ≥ 1000 HU respectively. All patients underwent ESWL, and the stone crushing rate, the sessions of lithotrispy and shock wave number were recorded and compared among the three groups. Results The low-density group had the lowest invalid rate, calculi residual rate, and the highest efficiency rate, the comparison of the invalid rate, calculi residual rate and efficiency rate among three groups showed a significant difference, moreover the paired comparison showed statistic difference(P<0.05). The stone free rate of the lowdensity group was the highest, which was significantly higher than that of the middle and high-density group(P<0.05), no statistic difference was found between the middle and high density group(P>0.05). The shock wave number, sessions of lithotrispy and CT values was lowest in the low-density group, the difference of the three groups was significant, and the paired comparison had statistically significant difference(P<0.05). Conclusion The curative effect of ESWL for renal stone varies with the CT value, suggesting that the application of NCCT can predict the curative effect of ESWL, and provide a theoretical basis for the treatment of renal stone.
【关键词】非增强CT值;预测;体外冲击 波碎石术;肾结石
【中图分类号】R692.4
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.06.025
前言
肾结石是泌尿外科常见疾病,临床男性发病率略高于女性,青壮 年较为多发,两侧肾脏无明显差异,90%结石含钙,主要以草酸钙形 式存在[1]。肾结石患者中40%~75%存在着不同程度的腰痛,结石体积 相对较大,移动范围小,以腰部酸胀不适为主要表现,体力活动时加 重[2]。自上世纪80年代ESWL一直是治疗肾结石的主要方法,国内外大 量报道均证实ESWL治疗高效、安全,具有非侵入的优点,创伤小且恢 复时间短[3]。但多种原因均会对ESWL治疗效果产生影响,结石密度、 碎性、组成成分、位置、大小等均会影响碎石效果。例如黄苏溪等[4] 报道ESWL治疗直径10~20mm的输尿管上段结石碎石成功率处于60~90% 之间;刘志敏等[5]认为结石硬度越大,碎性越差ESWL治疗越难击碎。 CT检查逐渐向快速、安全、高分辨率方向发展,非增强CT在泌尿外科 领域中对泌尿系统结石诊疗评估具有十分重要的意义[6]。目前国内运 用CT值对泌尿系统结石进行量化预测的报道还较为缺乏,本文探究非 增强CT值在预测体外冲击波碎石术(ESWL)治疗肾结石的应用价值研 究,为体外冲击波碎石疗效预测提供理论依据,报道如下。
中国CT和MRI杂志
第16卷, 第 6 期
2018年06月
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