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静脉内平滑肌瘤延 伸到下腔静脉和心 脏的CT诊断

作者:郭玉峰1 范 淼2 朱俊峰3 杨有优2

所属单位:1.广东医科大学附属医院妇产科 (广东 湛江 524001) 2.中山大学附属第一医院放射科 (广东 广州 510080) 3.中山大学附属第一医院病理科 (广东 广州 510080)

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摘要

目的 静脉内平滑肌瘤病延伸到 下腔静脉和心脏是手术治疗面临的一个难 题。我们探讨使用CT血管造影在该类疾病 术前评估中的应用。方法 复习从2010到 2017年4例静脉内平滑肌瘤延伸到下腔静 脉和心脏病例,研究其术前CT征象及与外 科手术的关系。结果 结合临床病史和CT 征象,所有病人均得到正确诊断。其中3 例肿瘤局限于下腔静脉,1例肿瘤突入右 心房、右心室、肺动脉。所有病人均有多 发盆腔软组织肿块,经髂静脉延伸到下腔 静脉,并均见肺内转移。所有病例均经包 括血管外科、妇科、心脏外科合作成功手 术,未出现严重并发症与死亡。结论 CT 血管造影可准确提示静脉内平滑肌瘤病的 位置、大小、全部病变的延伸范围以利术 前评估,在制定手术计划和获得良好预后 方面有重要意义。

Objective Intravenous leiomyomatosis extending to inferior vena cava and heart is one of the most challenging conditions for surgical treatment. We explored the use of CT in preoperative assessment for this disease. Methods 4 patients with intravenous leiomyomatosis extending to inferior vena cava and heart were reviewed from the year 2010 to 2017, focusing on the CT finding characteristics and surgical procedures in clinical treatment. Results All patients were diagnosed correctly combining the clinical medical history and CT imaging. 3 patients had tumors confined within the inferior vena cava, and 1 patient had tumors intruding into the right atrum, the right ventricle and the pulmonary artery. All patients had multiple pelvis soft masses extending into inferior vena cava throght the iliac veins, and had tumors invading into lung. All operations were successfully performed by cooperation including gynecology , cardiac surgery, and vascular surgery, without severve complications or deaths. Conclusion CT imging can present lacation, size, and full-scale extension of intravenous leiomyomatosis lesions, and can be used as first-line imaging technique in preoperative assessment, having great significance in making surgical plan and obtaining successful outcome.

【关键词】静脉内平滑肌瘤;下腔静脉;

【中图分类号】R322.1+1

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.06.002

前言

静脉内平滑肌瘤病是一种非常罕见、来源于平滑肌瘤的疾病。其 起自子宫平滑肌瘤,或子宫静脉的平滑肌层,属组织学上良性,行为 学上具有侵袭性的血管内肿瘤。该种肿瘤最初发现于子宫静脉,可达 下腔静脉、右心腔,甚至肺动脉[1-2]。因其极少,且病人通常无症状, 通常直到肿瘤延伸到心脏才被发现,早期诊断困难且少见报道。   由于该类肿瘤延伸范围较广,甚至达心腔,其外科完全切除治疗 具有较大难度,及早诊断和全面的术前评估非常重要。本研究的目的 就是评估CT在显示肿瘤延伸范围、制定外科计划中的价值。