目的 观察超声联合MRI多定量 参数在诊断乳腺癌中的应用价值。方 法 对120例拟诊为乳腺癌患者的临床资 料进行回顾性分析，均接受超声、MRI检 查，以病理检查为“金标准”，评估超 声、MRI及二者联合检查对乳腺癌诊断的 灵敏度、特异度、准确度、阳性及阴性 预测值，观察MRI多定量参数[表观扩散 系数(ADC)、T波峰(Tpeak)、早期强化率 (EER)、峰值强化率(PER)]在乳腺良恶性 病变间的差异。结果 MRI诊断乳腺恶性病 变ADC、Tpeak值均低于良性病变，EER、 PER值则均高于良性病变(P＜0.05)。超 声、MRI及超声联合MRI诊断乳腺癌灵敏 度、特异度、阳性预测值、阴性预测值 无明显差异(P＞0.05)。超声联合MRI诊 断乳腺癌准确度高于超声(P＜0.05)。结 论 超声、MRI诊断乳腺癌均具有较高的 灵敏度、特异度、准确度，图像特点明 显，超声联合MRI多定量参数有助于降低 漏诊、误诊率，提高诊断准确度。

Objective To observe the application values of ultrasound combined with MRI multiple quantitative parameters in the diagnosis of breast cancer. Methods The clinical data of 120 cases of patients diagnosed as breast cancer were retrospectively analyzed, and all patients were given ultrasound and MRI examination. The pathological examination was taken as the "gold standard", and the sensitivity, specificity, accuracy, positive and negative predictive values of ultrasound, MRI and two combined examinations were evaluated in the diagnosis of breast cancer, and the differences of MRI multiple quantitative parameters [apparent diffusion coefficient (ADC), T peak (Tpeak), early enhancement rate (EER), peak enhancement rate (PER)] in benign and malignant breast lesions were observed. Results The values of ADC and Tpeak in the diagnosis of malignant breast lesions were lower than those of benign lesions by MRI while the values of EER and PER were higher than those of benign lesions (P<0.05). There was no significant difference in the sensitivity, specificity, positive predictive value and negative predictive value of ultrasound, MRI and ultrasound combined with MRI in the diagnosis of breast cancer (P>0.05). The diagnostic accuracy of ultrasound combined with MRI was higher than that of ultrasound (P<0.05). Conclusion Ultrasound and MRI can have high sensitivity, specificity and accuracy, and obvious image features. Ultrasound combined with MRI multiple quantitative parameters can help reduce the misdiagnosis rate and missed diagnosis, and enhance the diagnostic accuracy.