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MRI检查胎盘植入高 危患者的结果分析 及影像学表现

作者:赵 毅 万 军

所属单位:河南省永城市人民医院影像科 (河南 永城 476600)

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摘要

目的 对磁共振(MRI)检查胎盘 植入高危患者进行诊断结果及影像学表 现分析,为胎盘植入的MRI诊断提供理论 依据。方法 本组观察对象为2015年12 月-2016年12月于我院诊断的70例胎盘植 入高危患者,所有患者入组后均行常规 MRI检查,详细记录MRI图像分析结果,以 手术或病理诊断结果为金标准,分析MRI检 查胎盘植入以及粘连型胎盘、穿透型胎 盘、植入型胎盘三种分型的诊断敏感度与 特异性,分析部分患者MRI图像的影像学 表现。结果 胎盘植入MRI影像学表现主要 有子宫肌层与胎盘分界不清;局部子宫壁 变薄;T2WI图像显示胎盘内有黑条带信 号;子宫下部膨隆不齐;子宫与胎盘交界 面存在多发纡曲血管影;子宫壁与胎盘交 界处出血或血肿;膀胱壁中断;MRI诊断 无胎盘植入40例、粘连型胎盘植入6例、 植入型胎盘植入19例、穿透型胎盘植入5 例;手术或病理诊断无胎盘植入37例、粘 连型胎盘植入13例、植入型胎盘植入17 例、穿透型胎盘植入3例;总体胎盘植入 诊断敏感度为66.67%,特异度为83.78%, Youden指数为0.50,粘连型胎盘植入诊 断敏感度为46.15%,特异度为98.25%, Youden指数为0.44,植入型胎盘植入诊 断敏感度为82.35%,特异度为90.57%, Youden指数为0.73,穿透型胎盘植入诊 断敏感度为66.67%,特异度为95.52%, Youden指数为0.61。结论 MRI检查胎盘植 入高危患者具有多种特征性影像学表现, 对于植入型胎盘植入具有较高的诊断敏感 度,MRI可用于高危患者胎盘植入的初步 诊断。

Objective To analyze the diagnostic results and imaging findings of high risk patients with placenta accreta by magnetic resonance imaging (MRI), and to provide theoretical basis for MRI diagnosis of placenta accreta. Methods The objects of this study were 70 patients with high risk of placenta accreta diagnosed in our hospital from December 2015 to December 2016, all patients underwent routine MRI examination after selection, and the results of MRI image analysis were recorded in detail. The diagnostic sensitivity and specificity of three types of placenta accreta, namely adhesive placenta, penetrating placenta, and implanted placenta, were analyzed by using results of MRI or pathological diagnosis as the gold standard. The imaging findings of MRI in some patients were analyzed. Results The MRI imaging findings of placenta accreta mainly showed that the unclear demarcation between myometrium and placenta, and the thinning of local uterine wall. T2WI images showed there were black stripes in the placenta, the lower part of the uterus was bulging, the uterus and placenta interface had multiple tortuous vascular, and bleeding or hematoma happened at the junction of the uterine wall and placenta, and bladder wall were interrupted. There were 40 cases of placenta free accreta, 6 cases of adhesive placenta accreta, 19 cases of implanted placenta accreta and 5 cases of penetrating placenta accreta diagnosed by MRI. There were 37 cases of placenta free implantation, 13 cases of adhesive placenta accreta, 17 cases of implanted placenta accreta and 3 cases of penetrating placenta implantation diagnosed by pathological diagnosis. The overall diagnostic sensitivity of placenta accreta was 66.67%, with a specificity of 83.78%, the Youden index was 0.50. The sensitivity, specificity and Youden index of adhesive placenta accreta were 46.15%, 98.25%, 0.44, respectively. The diagnostic sensitivity of implanted placenta accreta was 82.35%, specificity was 90.57%, and Youden index was 0.73. The diagnostic sensitivity, specificity and Youden index of penetrating placenta accreta were 66.67%, 95.52%, 0.61, respectively. Conclusion High risk patients with placenta accreta by MRI has a variety of characteristics of imaging findings, MRI has higher diagnostic sensitivity for implanted placenta, and can be used for the preliminary diagnosis of placenta accreta in high-risk patients.

【关键词】MRI;胎盘植入高危患者;诊 断结果;影像学表现

【中图分类号】R714.46+2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.03.030

前言

由于宫腔手术史、前置胎盘、剖宫产史及经产妇等危险因素的增 加,我国胎盘植入的发病率呈逐年上涨趋势,其病理机制为各种因素 所引起的子宫与胎盘之间的底蜕膜层缺失或减少[1],胎盘与子宫肌层 存在直接贴附的关系,严重者甚至穿透子宫肌层,不及时诊断与干预 治疗可造成子宫穿孔、产后大出血等严重并发症,因此产前及时的准 确诊断极为重要,同时其能够为手术方案的确定以及合适的分娩方式 的选择提供理论依据[2]。临床上对于胎盘植入的分型主要依据胎盘绒 毛植入子宫壁的深浅程度判断,分为植入型胎盘植入、粘连型胎盘植 入以及穿透型胎盘植入3种类型,有报道[3]称植入型比例最高。目前在 诊断胎盘植入方面尚缺少特征性的实验室检测项目以及显著的临床表 现,难以在产前给予准确的诊断,需要借助超声、MRI等影像学检查给 予辅助诊断[4]。超声检查运用历史较长,临床医师经验丰富,是诊断 产科疾病中一种有效的检查方法,但随着MRI成像技术不断提高,临床经验不断提升,MRI已成为继超 声检查之外的另一种高效检查方 法。现对磁共振(MRI)检查胎盘植 入高危患者进行结果及影像学表 现分析,为胎盘植入的MRI诊断提 供理论依据,报道如下。