目的 探讨MSCT与超声对结节性 甲状腺肿的诊断价值。方法 收集2014年 12月-2016年12月期间来我院就诊的68例 结节性甲状腺肿患者，分别采用MSCT与超 声对结节性甲状腺肿进行诊断，观察MSCT 和超声两者诊断的结果，并与临床病理检 查结果进行分析比较，评估两种鉴别方 法的灵敏度、特异性及准确率。结果 本 组68例患者中，属于恶性结节19例，包 括乳头状癌9例，滤泡细胞癌6例，髓样癌 5例；良性结节49例，34例合并囊性变， 10例合并间质纤维化，5例合并出血及感 染。临床病理诊断为恶性结节19例，良性 结节49例；超声诊断为恶性12例，良性 56例；MSCT诊断恶性结节20例，良性48 例。超声诊断的灵敏度(84.65%)、特异性 (77.57%)、准确率(82.35%)优于MSCT的灵 敏度(75.55%)、特异性(65.29%)、准确率 (70.58%)，两种诊断方式之间差异有统计 学意义(P<0.05)。结论 超声诊断结节性 甲状腺肿的灵敏度、特异性以及准确率均 优于MSCT检查。

Objective To investigate the value of MSCT and ultrasonography in the diagnosis of nodular goiter. Methods The CT and ultrasound data of 68 patients with nodular goiter in our hospital during the period of December ~2016 December 2014 were collected, and the results were compared with clinical pathological examination, and the sensitivity, specificity and accuracy of the two methods were evaluated. Results Among 68 patients, there were 19 cases of malignant nodules, included papillary carcinoma in 9 cases, follicular carcinoma in 6 cases, and medullary carcinoma in 5 cases. There were 49 cases of benign nodules and cystic fibrosis in the other 34 cases, and there were interstitial fibrosis in 10 cases, hemorrhage and infection in 5 cases. Clinical pathological diagnosis of 19 cases of malignant nodules, benign nodules in patients with ultrasound diagnosis of malignant in 12 cases, benign in 56 cases. MSCT diagnosis of malignant nodules in 20 cases,benign in 48 cases. The sensitivity of ultrasound diagnosis(84.65%), specificity(77.57%) and accuracy (82.35%) were better than MSCT with the sensitivity(75.55%), specificity(65.29%) and accuracy(70.58%), there was significant difference between the two diagnostic methods(P<0.05). Conclusion The sensitivity, specificity and accuracy of ultrasonic diagnosis of nodular goiter are superior to that of MSCT.