目的 分析多层螺旋CT灌注成像 在肾透明细胞癌中的应用价值。方法 选 取2015年2月至2017年3月在我院治疗的 肾透明细胞癌患者124例(观察组)，同时 选取健康志愿者120例作为对照组，均进 行多层螺旋CT灌注成像检查，分析感兴趣 区血流量(BF)、血容量与主动脉血容量 比值(BV/A)、平均通过时间(MTT)和表面 通透性(PS)。结果 观察组BV/A、BF和PS 分别为(0.16±0.03)、(324.53±90.15) ml/min- 1·100g- 1和(45.52±16.54) ml/min-1·100g-1，明显低于对照组(P ＜0.05)；观察组和对照组MTT比较差异 无统计学意义(P＞0.05)；观察组Ⅲ-Ⅳ 期患者BV/A和PS分别为(0.29±0.07)和 (60.13±12.25)，明显高于Ⅰ期和Ⅱ期 患者(P＜0.05）；Ⅲ-Ⅳ期和Ⅱ期患者BF 分别为(361.51±92.22)ml/min-1·100g-1 和(387.22±84.16)ml/min-1·100g-1，明 显高于Ⅰ期患者(P＜0.05)；不同Robson 分期患者MTT比较差异无统计学意义(P ＞0.05)；观察组不同年龄、性别患者 CT灌注参数比较差异无统计学意义(P＞ 0.05)。结论 多层螺旋CT灌注成像在肾透 明细胞癌诊断中有一定应用价值，可为临 床分期提供依据。

Objective To investigate the application value of multi-slice spiral CT perfusion imaging in renal clear cell carcinoma. Methods A total of 124 patients with renal clear cell carcinoma treated in our hospital from February 2015 to March 2017 were selected (observation group), and 120 healthy volunteers were selected as control group, multislice spiral CT perfusion imaging was performed to analyze the blood flow (BF), blood volume and aortic blood volume ratio (BV/A), mean transit time (MTT) and permeability surface (PS) in the areas of interest. Results The observation group BV/A, BF and PS were (0.16±0.03), (324.53±90.15) mL/min-1·100g-1 and (45.52±16.54) mL/min1 ·100g-1, significantly lower than the control group (P<0.05). The observation group and the control group MTT had no significant difference (P>0.05). The observation group BV/A and PS in patients with III-IV stage were (0.29±0.07) and (60.13±12.25) mL/min-1·100g-1, were significantly higher than that of patients with stage I and II (P < 0.05). BF in patients with III-IV stage and II stage were (361.51±92.22) mL/min1 ·100g-1 and (387.22±84.16) mL/min-1·100g-1, significantly higher than the patients with stage I (P<0.05). There were no statistically significant differences in MTT between different Robson stages(P>0.05). There were no significant difference in CT perfusion parameters between different age and genders of observation group (P>0.05). Conclusion Multi-slice spiral CT perfusion imaging has a certain value in the diagnosis of renal clear cell carcinoma and it can provide the basis for clinical staging.