简体中文

论著-头颈部

乏脂肪肾血管平滑 肌脂肪瘤与肾癌DWI 信号特点及病灶表 面扩散系数分析

作者:吴 锦1 覃 艳2 邓士杰1

所属单位:1.解放军第163医院影像科 (湖南 长沙 410003) 2.中南大学湘雅医院放射科 (湖南 长沙 410008)

PDF

摘要

目的 研究乏脂肪肾血管平滑 肌脂肪瘤(RAML)和肾癌的弥散加权成像 (DWI)信号特点及病灶表面扩散系数(ADC) 的关系。方法 选取2014年2月至2016年7 月经我院病理确诊且具有完整MRI检查资 料的乏脂肪RAML患者30例设为观察组。 另取同期病理确诊具有完整MRI检查资料 的肾癌患者30例设为对照组。分别对比 两组患者基本资料、DWI信号特点以及 ADC值。结果 观察组年龄为(47.5±6.2) 岁,显著低于对照组的(63.4±7.3)岁, 差异有统计学意义(P<0.05)。观察组DWI 信号特点为低、稍高信号,而对照组DWI 表现为不均匀高信号。观察组ADC值为 (1.622±0.183)×10-3mm2 /s,显著高于对 照组的(1.454±0.282)×10-3mm2 /s,差异 有统计学意义(P<0.05)。结论 ADC值可 作为临床上诊断乏脂肪RAML与肾癌的新指 标,具有较高的应用价值。

Objective To study the relationship between the characteristics of diffuse weighted imaging of renal cell carcinoma(RCC) and renal angiomyolipomas(RAML) with minimal fat and the surface diffusion coefficient (ADC) of the lesions. Methods A total of 30 cases of RAML patients with complete MRI examination data were set as observation group, and another 30 patients with RCC were set as the control group from February 2014 to July2016 in our Hospital. The patients' basic information, DWI signal characteristics and ADC values were respectively compared between the two groups. Results The age of the observation group was (47.5+6.2) years, which was significantly lower than that of the control group (63.4+7.3) years old, and the difference was statistically significant (P<0.05). The characteristics of the DWI signal in the observation group were low and slightly high, while the DWI signal in the control group was unevenly high. The observation group ADC=(1.622+0.183)×10-3mm2 /s, significantly higher than the control group (1.454+0.282)×10-3mm2 /s, the difference was statistically significant(P<0.05). Conclusion The value of ADC can be used as a new index for clinical diagnosis of RAML with minimal fat and renal cancer. It is of high application value.

【关键词】乏脂肪肾血管平滑肌脂肪瘤; 肾癌;弥散加权成像;表面扩 散系数

【中图分类号】R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.03.028

前言

乏脂肪肾血管平滑肌脂肪瘤(Renal angiomyolipomas,RAML)主 要是指RAML中不含脂肪成分或含有少量脂肪的一组疾病,属于较为常 见的肾脏良性肿瘤[1]。而临床上乏脂肪RAML的多种影像学结果与肾癌 存在较高的相似度,从而为临床诊断增加了难度,易导致误诊、误 治,一旦误诊采取了手术切除对患者的身心将造成一定影响[2]。近年 来,随着影像学技术的不断进步,扩散加权成像(Diffusion weighted imaging,DWI)开始应用于全身多个脏器中[3],具有一定的参考价 值。国内外不少研究报道也将表面扩散系数(Apparent diffusion coefficient,ADC)值作为研究肾脏疾病的一种新指标[4]。本文通过研 究乏脂肪RAML和肾癌的DWI信号特点及病灶ADC值之间的相关性,目的 在于为临床乏脂肪RAML与肾癌的鉴别提供参考依据。