论著-头颈部
CT与MRI在诊断原发 性肝癌介入术后病 灶残留及复发中的 应用价值
作者:朱风叶 李 红 乔继红 王全华
所属单位:河南省驻马店市中心医院放射科 (河南 驻马店 463000)
PDF摘要
目的 探讨电子计算机断层扫描 (Computed Tomography,CT)与核磁共振 (Magnetic Resonance Imaging,MRI) 在诊断原发性肝癌(primary hepatic carcinoma,PHC)介入术后病灶残留及复 发中的应用价值。方法 选取本院2015 年6月-2017年6月收治的PHC患者60例为 研究对象,共84个病灶,患者均在行经 导管肝动脉化疗栓塞术(transarterial chemoembolization,TACE)后2-6个月来 院复查,采用CT、MRI和数字减影血管造 影(Digital Subtraction Angiography, DSA)检查。以DSA为金标准,比较CT和 MRI检查对术后病灶残留、复发诊断的准 确度、敏感度、特异度,以及对病灶肿 瘤包膜的检出率。结果 CT病灶残留或复 发诊断准确度、敏感度、特异度分别为 79.76%、72.58%和100.00%,MRI病灶残留 或复发诊断准确度、敏感度、特异度分别 为94.05%、91.94%和100.00%,MRI诊断的 准确度和敏感度显著高于CT(P<0.05);CT 肿瘤包膜检出率为3.57%,显著低于MRI 肿瘤包膜检出率10.71%(P<0.05)。结论 MRI对于PHC患者TACE术后疗效诊断准确度 高,明显优于CT诊断。
Objective To explore the application value of CT and MRI in the diagnosis of the residual and recurrent lesion of primary liver cancer after interventional therapy. Methods A total of 60 cases of PHC patients treated in our hospital from June 2015 to June 2017 were selected for the study with a total of 84 lesions, and all the patients were given review after 2-6 months of the transarterial chemoembolization (TACE). The CT, MRI and digital subtraction angiography (DSA) were performed. The accuracy, sensitivity, specificity of the diagnosis of the residues and recurrence lesion and the detection rate of the capsule were analyzed by CT and MRI examination, by taking the DSA as the gold standard. Results The accuracy, sensitivity and specificity of lesion residues and recurrence were 79.76%, 72.58% and 100.00% respectively by CT and were 94.05%, 91.94% 100.00% by MRI, and the accuracy and sensitivity of MRI diagnosis were significantly higher than those by CT (P<0.05). The detection rate of the lesion tumor capsule by CT was significantly lower than that by MRI (3.57% vs 10.71%) (P<0.05). Conclusion MRI has the high accuracy of efficacy diagnosis for PHC patients after TACE, which is significantly better than the CT diagnosis.
【关键词】CT;核磁共振;原发性肝癌; 行经导管肝动脉化疗栓塞术; 病灶残留及复发
【中图分类号】R51;R73
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2018.03.024
前言
原发性肝癌(primary hepatic carcinoma,PHC)是我国中年以上 男性易发的恶性肿瘤之一,发病原因可能与病毒性肝炎、肝硬化、 化学致癌物质以及环境等因素相关。PHC患者一般表现为肝脏进行性 肿大、肝区疼痛、消瘦、乏力、呕吐、腹泻等症状[1-2]。手术根治性 切除是PHC治疗的最有效方法,但因PHC早期无明显临床症状、发病迅 速且易转移,许多患者临床确诊时已失去手术治疗机会[3]。对于无法 进行手术治疗的患者,行经导管肝动脉化疗栓塞术(transarterial chemoembolization,TACE)不仅可对肿瘤进行药物化疗,还可阻断 肿瘤动脉供血,对预后有积极作用,是目前PHC非手术治疗的首选方 法[4]。而PHC患者TACE术后疗效的评价也十分重要,以往常采用数字减 影血管造影(Digital Subtraction Angiography,DSA)和电子计算机断 层扫描(Computed Tomography,CT)技术评价治疗疗效,随着磁共振成 像(Magnetic Resonance Imaging,MRI)技术的发展和普及,其在TACE 术后疗效评估方面也得到广泛应用。本研究旨在比较CT和MRI对PHC患 者TACE术后病灶残留及复发等评估的应用价值,现报道如下。
中国CT和MRI杂志
第16卷, 第 3 期
2018年03月
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