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MRI联合MRCP对胆 囊癌及局部组织器 官侵犯诊断价值研 究

作者:孙 敏 张 磊 宋彦澄 董红焕 边 浩

所属单位:河北省沧州市中心医院磁共振成像 科 (河北 沧州 061000)

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摘要

目的 探讨磁共振(MRI)联合磁 共振胰胆管成像(MRCP)对胆囊癌及局部 组织器官侵犯诊断价值研究。方法 回顾 性分析我院收治132例拟诊胆囊癌患者临 床资料,患者均经手术病理或活检病理 确诊,其中胆囊癌114例,胆囊良性肿 物18例,患者均MRI、MRCP、多层螺旋 CT(MSCT)检查。比较MRI联合MRCP检查、 MRI检查、MSCT检查对胆囊癌及局部组织 器官侵犯的诊断价值。结果 MRI联合MRCP 检查诊断胆囊癌敏感性为96.5%稍高于 MRI90.4%、MSCT86.0%(P>0.05);MRI联 合MRCP检查诊断胆囊癌特异性为88.9%高 于MRI72.2%、MSCT55.6%(P<0.05);MRI 联合MRCP检查诊断胆囊癌误诊率为11.1% 低于MRI27.8%、MSCT44.4%(P<0.05); MRI联合MRCP检查、MRI检查对胆管受 侵、肝脏直接受浸、肝门淋巴结受侵的 诊断敏感性分别高于MSCT(P<0.05), MRI联合MRCP检查对上述组织侵犯的诊 断敏感性稍高于MRI检查(P>0.05);三 组检查方法对胰腺受浸润诊断敏感性无 统计学差异(P>0.05);MRI联合MRCP检 查、MRI检查诊断胆囊癌临床分期结果符 合率分别为95.6%、93.9%高于MSCT检查 79.8%(P<0.05);MRI联合MRCP检查诊断 胆囊癌临床分期结果符合率稍高于MRI检 查(P>0.05)。结论 MRI联合MRCP对胆 囊癌诊断效果佳,其特异性、敏感性均 较高,准确评估肿瘤局部浸润范围,临 床分期结果符合率也较高,值得临床选 择。

Objective To investigate the diagnostic value of magnetic resonance imaging (MR) combined with MR cholangiopancreatography (MRCP) in gallbladder carcinoma and local tissue and organ invasion. Methods The clinical data of 132 patients with gallbladder carcinoma were retrospectively analyzed. The patients were diagnosed by pathology or biopsy. There were 114 cases of gallbladder carcinoma and 18 cases of gallbladder benign tumor. All patients were MRI, MRCP, MSCT examination. The diagnostic value of MRI combined with MRCP, MRI, MSCT in gallbladder carcinoma and local tissue and organ invasion were compared. Results The sensitivity of MRI combined with MRCP in the diagnosis of gallbladder carcinoma was 96.5% higher than that of MRI 90.4% and MSCT86.0% (P>0.05). MRI combined with MRCP examination of gallbladder carcinoma specificity was 88.9% higher than MRI 72.2%, MSCT55.6% (P <0.05). MRI combined with MRCP examination of gallbladder cancer misdiagnosis rate was 11.1% lower than MRI 27.8%, MSCT44.4% (P<0.05). The diagnostic sensitivity of MRI combined with MRCP and MRI in the diagnosis of bile duct invasion, direct liver infiltration and hepatic portal lymph node invasion were higher than that of MSCT (P <0.05). MRI and MRCP examination of the above-mentioned tissue invasion of the diagnostic sensitivity slightly higher than the MRI examination (P>0.05). There was no significant difference in the sensitivity of pancreatic infiltration in the three groups (P>0.05). MRI combined with MRCP examination, MRI examination of gallbladder cancer clinical staging rate was 95.6%, 93.9% higher than the MSCT examination 79.8% (P<0.05). MRI combined with MRCP examination of gallbladder cancer clinical staging rate was slightly higher than that of MRI (P>0.05). Conclusion MRI combined with MRCP is effective in the diagnosis of gallbladder carcinoma. Its specificity and sensitivity are high, and the local infiltration range is evaluated accurately. The coincidence rate of clinical stage is also high, which is worthy of clinical choice.

【关键词】MRI;MRCP;胆囊癌;局部组 织器官;诊断价值

【中图分类号】R735.8

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.03.023

前言

胆囊癌是临床上较为多见的恶性消化道肿瘤之一,其发病率高, 早期症状隐匿,一旦发现多存在局部组织器官侵犯,预后常不佳[1-3]。 因此,早期发现、选择诊断敏感性较高的影像学方法对患者治疗和预 后具有重要意义。超声是胆囊病变的首选检查方法,但其对胆囊癌局 部组织浸润范围显示较差,螺旋CT因扫描速度快、软组织分辨率高, 常被用于诊断胆囊癌。MRI的诊断效能已逐渐超过螺旋CT,可有效评价 胆囊癌局部组织侵袭范围及脏器转移[4-6],MRCP可三维立体、多角度显 示胆囊形态、胆管解剖结构,对胰管的病变也显示较佳。但以往研究 多集中在超声、螺旋CT检查诊断胆囊癌,关于MRI联合MRCP在该疾病的 诊断研究报道则较少。本研究探讨MRI联合MRCP对胆囊癌及局部组织器 官侵犯诊断价值,现报道如下。