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肝内胆管囊腺癌的 CT诊断及鉴别

作者:林观生1 马周鹏1 陈炳叶2 朱建忠3

所属单位:1.上海市金山区中西医结合医院放 射科 2.上海市金山区中西医结合医院普 外科 (上海 201501) 3.泰山医学院附属医院影像中心 (山东 泰山 271000)

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摘要

目的 分析肝内胆管囊腺癌的CT 表现,以提高诊断水平。方法 回顾性分 析7例经手术及病理证实的肝内胆管囊腺 癌的CT资料。结果 7例均为单发囊性肿 瘤,位于肝左叶4例,肝右叶2例,1例累 及左、右叶。3例局限于肝内,4例突出肝 外。肿瘤最大直径约(4.8-18.5)cm,2例 单房类圆形,5例多房不规则分叶状。3例 边界较清晰,4例局部边界不清。平扫囊 壁均厚薄不均,6例见较明显壁结节,2例 囊壁钙化。多房者囊内分隔粗细不一,2 例巨大肿瘤囊内见较低密度实性成分。5 例囊液密度不均,CT值约(11-29)HU,2例 密度较均匀,CT值约(4-8)HU。增强7例囊 壁、分隔动脉期轻度强化,门脉及延迟期 呈持续不均匀中度强化;5例壁结节持续 延迟强化,1例壁结节动脉期不均匀较明 显强化,门脉及延迟期强化减弱。3例邻 近肝内胆管轻度扩张,2例胆总管轻度扩 张,1例腹腔及腹膜后多发淋巴结肿大,2 例出现腹腔积液。结论 肝内胆管囊腺癌 的CT表现具有一定特征,认识其影像特征 对诊断及鉴别诊断具有重要价值。

Objective To explore the CT characteristics of intrahepatic biliary cystadenocarcinoma and improve the diagnostic level. Methods Analyze he CT data of 7 cases of intrahepatic biliary cystadenocarcinoma which confirmed by surgery and pathology retrospectively. Results All of the 7 cases were single cystic tumors, 4 cases in the left lobe of the liver, 2 cases of the right lobe of the liver, and 1 cases involving the left and right leaves. 3 cases were confined inside the liver while 4 cases were out of the hepatic outline. The maximum diameter of all tumors was 4.8 to 18.5 cm , 2 cases were single cavity and with oval shape, 5 cases were multiple cavities and showed irregular shape and with lobes. The boundary of 3 cases were clear while the rest 4 cases were unclear. The wall of the cystic wall of the lesion was uneven on unenhanced CT, the cystic wall of all 7 tumors were heterogeneous in thickness, obvious wall nodules can be seen in 6 tumors, spotted calcification of cystic wall can be seen in 2 tumors. The septum inside multiple cavities were heterogeneous in thickness, a little of solid tissue with mild low density can be seen in 2 cases of huge tumors. The cyst fluid of 5 tumors showed heterogeneous density and the CT value were 11-29HU while the rest 2 tumors showed uniform density and the CT value were 4-8HU. On enhanced CT, the cystic wall and septum showed mild enhancement in artery phase, and continued heterogeneous moderate enhancement in portal vein and delayed phase; the wall nodules of 5 cases showed delayed enhancement continuously, while the wall nodules of 1 tumor showed obvious enhancement unevenly in artery phase, and the enhancement decreed in portal vein and delayed phase. Adjacent intrahepatic biliary of 3 tumors showed mild enlargement, the common bile duct of 2 tumors showed mild enlargement, 1 tumor accompanied with multiple swollen lymph nodes in the abdominal cavity and retroperitoneum, ascites can be seen in 2 tumors. Conclusion The CT features of intrahepatic biliary cystadenocarcinoma are of certain characteristics. It is of great value to recognize the imaging features for diagnosis and differential diagnosis.

【关键词】肝脏;肿瘤;胆管囊腺癌;X 线计算机;体层摄影术

【中图分类号】R735.7;R814.42

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.03.022

前言

胆管囊腺癌是一种罕见的恶性上皮性肿瘤,其中位于肝内者仅占 肝脏恶性肿瘤的0.41%[1-2],不足肝囊性肿瘤的5%[3]。因临床罕见并缺 乏特异症状及肿瘤指标,有时易与肝脏其他囊性病变混淆而误诊。笔 者回顾性分析7例经手术及病理证实的肝内胆管囊腺癌(intrahepatic biliary cystadenocarcinoma,IBC)的CT与临床资料,并复习相关文 献,旨在提高对其诊断水平。