简体中文

论著-头颈部

儿童闭塞性细支气 管炎的临床特征及 CT影像表现分析

作者:张义堂1 王中晓2 杨 红1 张伟东1 吕亚洲1 刘 平1

所属单位:1.郑州大学附属医院/南阳市中心 医院PICU (河南 南阳 473000) 2.河南省南阳医学高等专科学校护 理系 (河南 南阳 473000)

PDF

摘要

目的 探讨儿童闭塞性细支气管 炎的临床特征及CT影像表现。方法 回顾 分析我院儿科60例闭塞性细支气管炎患 儿临床资料,所有患儿均接受肺部CT检 查,分析患儿临床表现及CT图像特征。 结果 临床症状:持续性咳嗽、气促,伴 呼吸困难者32例(53.3%),伴间断发热 者39例(65.0%),伴活动后气促者28例 (46.7%);体征检查:肺部均可闻及干湿 啰音者37例(80.4%);可闻及喘鸣音者44 例(73.3%),合并三凹征者28例(46.7%); 肺部CT检查显示存在马赛克灌注征者43例 (71.7%),单侧透明肺者3例(5.0%),支 气管壁增厚者20例(33.3%),合并肺不张 者6例(10.0%),合并支气管扩张者13例 (21.7%),支气管粘液栓4例(6.7%)。结 论 肺部CT可较清楚地显示小气道的形态 学变化特点,较病原学检查、肺功能检测 具有无创、精确、可重复等优点,为临床 诊断提供一定参考价值。

Objective To explore the clinical features and CT imaging of bronchiolitis obliterans in children. Methods The clinical data of 60 children with bronchiolitis obliterans in the department of pediatrics of our hospital were retrospectively analyzed. All the children were given the pulmonary CT examination, and the clinical manifestations and CT imaging features were analyzed. Results In terms of clinical symptoms, there were 32 cases (53.3%) of patients with persistent cough, shortness of breath and dyspnea, and 39 cases (65.0%) with intermittent fever and 28 cases (46.7%) with shortness of breath after activities. From the respect of physical examination in the lungs, there were 37 cases (80.4%) of dry and wet rales, and 44 cases (73.3%) with wheezing rales and 28 cases (46.7%) with combined three depressions sign. Pulmonary CT examination showed that there were 43 cases (71.7%) of patients with mosaic perfusion, 3 cases (5.0%) with unilateral transparent lung, 20 cases (33.3%) with bronchial wall thickening, 6 cases (10.0 %) with combined pulmonary atelectasis, 13 cases (21.7%) with combined bronchial dilatation and 4 cases (6.7%) with bronchial mucus. Conclusion Pulmonary CT can clearly show the small airway morphological changes, and has the noninvasive, accurate and repeatable advantages compared with the pathogen examination and pulmonary function test, and it can provide a certain reference value for the clinical diagnosis.

【关键词】儿童;闭塞性细支气管炎;临 床特征;CT表现

【中图分类号】R562.2 R814.42

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2018.03.013

前言

闭塞性细支气管炎(bronchiolitis obliterans,BO)是一种与小 气道炎症损伤相关的慢性纤维化肺阻塞性疾病[1],其诱发因素颇多, 如感染、结缔组织病、异体移植、吸入有毒物质、胃食管反流、药物 副作用等均可引起细支气管上皮细胞和上皮下结构发生炎症损伤,引 起细支气管炎[2]。儿童因抵抗力差,常因下呼吸道感染引起肺细支气 管发生狭窄或闭塞,表现为反复咳嗽、进行性呼吸困难,或活动后气 促[3]。因患儿早期临床特征及肺部X线片缺乏特异性,易与支气管哮 喘、支气管肺炎等疾病相混淆,本研究对我院儿科诊断为BO的46例患 儿临床表现进行回顾性分析总结,旨在提高对本疾病的认识,做出早 期诊断。