目的 探讨OSAHS患者进行H-UPPP 手术同时配合减重有效治疗后上气道各 间隙脂肪含量的变化。方法 选取2009年 1月-2014年12月我院就诊重度OSAHS患者 20例，行H-UPPP术+3月有效减重有效治疗 的OSAHS患者,对其有效治疗前后分别行多 导睡眠呼吸监测、颈部多层螺旋CT(MSCT) 扫描及随机软件后处理重建，分析鼻咽脂 肪体积(NPFV)，口咽脂肪体积(OPFV)，喉 咽脂肪体积(LPFV)，颈部皮下脂肪体积 (NSFV)，舌体组织体积(TBTV)的变化。结 果 OSAHS患者治疗前后NPFV、LPFV值差异 无统计学意义；OPFV、NSFV值差异有统计 学意义；治疗前后TBTV值差异有统计学意 义。结论 1.OPFV、NSFV值治疗前后有明 显变化,考虑体积增加直接导致咽喉部软 组织增多，引起上气道狭窄，呼吸阻力增 高，进而加重OSAHS。2.NPFV、LPFV值治 疗前后差异无统计学意义，考虑该区域脂 肪增多，但无可以增加患OSAHS的风险的 直接证据。3.TBTV值有明显变化,考虑 3月H-UPPP手术+有效减重治疗对于舌体体 积有明显影响。MSCT可对H-UPPP术+3月有 效减重有效治疗的OSAHS患者治疗前后的 颈部脂肪体积变化作客观评价，有较高的 临床应用价值。

Objective To OSAHS patients with effective H - UPPP surgery and weight loss at the same time, studing the change of fat in each airway clearance on content were. Methods Selected 20 severe OSAHS patients beween 200901 to 201412 in our hospital , of the effective treatment is HUPPP + 3 months effective weight loss to patients, Before and after effective treatment, patients need PSG, guide and neck MSCT scanning, analysis of nasopharynx fat volume(NPFV)/oropharynx fat volume(OPFV)/ laryngealpharynx fat volume(LPFV)/neck subcutaneous fat volume(NSFV)and tongue body tissue volume(TBSV) changes. Results For OSAHS patients, more effective weight + H - march UPPP surgery before and after treatment, two groups of Statistical data, NPFV and LPFV were not statistically significant difference volume percentage of fat , and no obviously changed before and after the treatment; OPFVand NSFV were statistically significant difference volume percentage of fat, and had obviously changed; There was statistically significant difference before and after treatmentof TBSV, and had obviously changed before and after treatment. Conclusion 1.Before and after treatment, Statistical data of OPFV and NSFV had obviously changed, therefore, consider the fat gap increase lead to throat soft tissue increased, caused airway stenosis, respiratory resistance increased, aggravated OSAHS.2. Statistical data of NPFV and LPFV were rich, That had not obviously changed before and after treatment, so considered its regional fat increased no evidence ,it could increase the risk of OSAHS. 3 Before and after HUPPP + 3 months effective weight loss, Statistical data of TBTV had obviously changed, consided the treatment had significant effect to the tongue body volume. MSCT could do objective evaluation for neck fat volume changes of OSAHS patients with HUPPP + 3 months effective weight loss , and has certain clinical application.