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螺旋CT多期增强扫描在肾癌诊断中的临床应用

作者:王雪松 吴建刚 周 扬 扬小君

所属单位:四川省攀枝花市第二人民医院影像中心(四川 攀枝花 617068)

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摘要

目的 探讨螺旋CT多期增强扫描 对肾癌的临床诊断价值。方法 回顾性分 析本院2009年4月-2015年8月经病理证实 115例肾癌患者的CT影像资料,观察CT图 像表现,并以手术病理结果为对照,评价 螺旋CT多期增强扫描对肾癌分期、分型的 诊断价值。结果 CT诊断肾癌I期50例,II 期35例,III期20例,IV期10例,与手术 病理结果对照,诊断总符合率80.0%。不 同亚型肾癌患者CT平扫期、动脉期、实 质期、排泄期CT值比较差异有统计学意 义(P<0.05)。透明细胞癌动脉期、实质 期、排泄期CT值分别显著高于嫌色细胞 癌、乳头状癌(P<0.05)。乳头状癌平扫 期CT值为(42.9±8.6)HU,显著高于透明 细胞癌、嫌色细胞癌的(36.6±6.0)HU、 (35.7±5.3)HU,差异有统计学意义(P <0.05)。CT显示类圆形病灶84个;强化 模式:透明细胞癌以不均匀强化为主,嫌 色细胞癌以均匀强化为主。结论 螺旋CT 多期增强扫描因其密度、强化等特点对肾 癌分期诊断准确率较高,有助于肾癌临床 分型。

Objective To investigate the value of spiral CT multi-phase enhanced scan in the diagnosis of renal cancer. Methods The CT imaging data of 115 patients with renal cancer confirmed by pathology in our hospital between April 2013 and August 2015 were analyzed retrospectively. The CT findings were observed. With surgical and pathological results as control, the diagnostic value of spiral CT multi-phase enhanced scan in staging and typing of renal cancer was evaluated. Results CT diagnosis showed that there were 50 cases in stage I of renal cancer, 35 cases in stage II, 20 cases in stage III and 10 cases in stage IV. Compared with surgical and pathological results, the total coincidence rate was 80.0%. There were significant differences in CT values of plain scan phase, arterial phase, parenchymal phase and excretion phase between patients with different subtypes of renal cancer (P<0.05). The CT values of clear cell carcinoma in arterial phase, parenchymal phase and excretion phase were significantly higher than those of chromophobe cell carcinoma and papillary carcinoma (P<0.05). The CT value of papillary carcinoma in plain scan phase (42.9±8.6) HU was significantly higher than that of clear cell carcinoma and chromophobe cell carcinoma [(36.6±6.0) HU, (35.7±5.3) HU] (P<0.05). CT showed that there were 84 round lesions; In terms of enhancement pattern, clear cell carcinoma was with inhomogenous enhancement and chromophobe cell carcinoma with homogeneous enhancement. Conclusion Because of features such as density and enhancement, the accuracy rate of spiral CT multi-phase enhanced scan in diagnosis of clinical stage of renal cancer is high, which is helpful to the diagnosis of renal cancer.

【关键词】螺旋CT;多期增强扫描;肾 癌;分期;分型

【中图分类号】R445.3;R737.11

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.06.030

前言

临床上原发性肾恶性肿瘤以肾癌为主,占80%以上,发病较隐匿, 1/2~3/5患者早期表现无特异性,多数临床发现时因体检或其他检 查[1]。为此提高肾癌早期检出率成为当下研究的重点。目前临床肾癌 以透明细胞癌、嫌色细胞癌等亚型为主,不同亚型生物学行为、预后 存在较大的差异。有研究[2]认为肾癌临床治疗方案制定、预后评估与 其分期、分型密切相关,术前正确判断肾癌分期、分型具有十分重要 的意义。多层螺旋CT(MSCT)具有扫描便捷、无创、重复性强、后处理 技术强大等特点,近年来在肾癌诊断中应用较多。且有报道称[3]螺旋 CT多期增强扫描在肾癌分期或分型诊断中有重要价值,但相关文献不 是很多。为了进一步证明螺旋CT增强扫描对肾癌分期、分型的诊断价 值,本研究以手术病理为对照,对本院2009年4月~2015年8月收治的 115例肾癌患者CT影像资料进行回顾性分析。现报告如下。