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肝外胆管癌超声造影和增强MRI影像学特征及诊断价值比较*

作者:李 拓

所属单位:南阳医学高等专科学校第一附属医院超声诊断科 (河南 南阳 473000)

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摘要

目 的 探讨并比较超声造影 (contrast-enhanced ultrasound,CEUS) 和增强MRI诊断肝外胆管癌(extrahepatic cholangoocarcinoma,EHCC)的影像学特 征及应用价值。方法 回顾性分析2014 年2月-2016年2月医院经手术确诊的78 例EHCC患者病例资料,均行CEUS和增强 MRI检查,分析其影像学特征及检查准 确率。结果 两种检查动脉期增强水平 比较差异无显著性(P>0.05),CEUS显 示门脉期、延迟期低增强的几率分别为 91.03%、100.0%高于增强MRI的10.26%、 8.97%(P<0.05);CEUS达到峰值时不均 匀增强几率和检查准确率与增强MRI比较 差异无显著性(P>0.05)。结论 CEUS、增 强MRI诊断EHCC均有特征性表现,且CEUS 可作为增强MRI诊断的有益补充,进一步 提高检查准确率。

Objective To investigate and compare the imaging features and diagnostic value of contrast-enhanced ultrasound (CEUS) and contrast-enhanced MRI in extrahepatic cholangiocarcinoma (EHCC). Methods The clinical data of 78 patients with EHCC confirmed by operation in our hospital between February 2014 and February 2016 were analyzed retrospectively. All patients underwent CEUS and contrast-enhanced MRI examination. The imaging features and the accuracy rates of examinations were analyzed. Results There was no significant difference in the level of enhancement in arterial phase between the two groups (P>0.05). The probabilities of low enhancement in portal vein phase and delay phase displayed by CEUS (91.03%, 100.0%) were higher than those of MRI (10.26%, 8.97%) (P<0.05). There were no significant differences between CEUS and MRI in inhomogeneous enhancement at peak value and the accuracy of detection (P >0.05). Conclusion The findings of CEUS and contrast-enhanced MRI are characteristic in the diagnosis of EHCC. CEUS can be used as a useful supplement to MRI diagnosis, further improving the diagnostic accuracy.

【关键词】肝外胆管癌;超声造影;磁 共振成像;增强;造影剂; 强化特点

【中图分类号】R445

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.06.024

前言

肝外胆管癌(EHCC)起源于胆管上皮,主要指发生于肝门区左右肝 管中壶腹部的恶性肿瘤,恶性程度高,且近年来发病率呈逐年上升趋 势[1]。根治性切除是EHCC的首选治疗方案,但因其解剖位置特殊,起 病隐匿,临床诊断难度较大,大部分就诊时已处于疾病中晚期,仅可 接受姑息性手术治疗,预后较差。MRI软组织分辨率高的特点,尤其是 增强MRI的应用,可清楚反映病灶血供特点、周围软组织受侵情况等, 对术前确定手术方案有指导意义[2]。超声造影(CEUS)可通过病灶区域 血流灌注情况明确肿瘤的边界、血管受侵等情况,在肝外胆管癌中具 有较高的应用价值。然而,目前CEUS和增强MRI用于诊断肝外胆管癌的 相关报道仍相对较少。对此,本文分析肝外胆管癌CEUS和增强MRI影像 学特征及诊断准确率,以提高早期肝外胆管癌诊断准确率,现报道如 下。