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增强CT在判断肺癌手术切除可行性中的价值*

作者:卢万里1 黄壮士2

所属单位:1.河南省南阳市中心医院胸外科 (河南 南阳 473000) 2.郑州大学第二附属医院胸外科 (河南 郑州 450014)

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摘要

目 的 探讨增强多层螺旋 CT(MSCT)在判断肺癌手术可切除性中的 应用价值。方法 回顾性分析2014年8 月-2016年8月我院经手术或活检病理确诊 的68例非小细胞肺癌(NSCLC)患者的增强 MSCT影像资料,并与手术结果对照。结 果 增强MSCT评估肺门、纵膈大血管受侵 犯及膈淋巴结转移与手术结果的一致性 分别为86.76%、83.82%,一致性比较满 意(Kappa=0.68、0.61),敏感度分别为 77.78%、80.0%,特异度分别为90.0%、 86.05%。增强MSCT评估NSCLC可切除性与 手术结果的一致性为79.41%,一致性比较 满意(Kappa=0.57),敏感度为85.37%,特 异度为70.37%。结论 增强MSCT可反映血 管受侵犯、纵膈淋巴结转移情况,为胸 外科医师判断NSCLC可切除性提供客观资 料。

Objective To investigate the application value of contrast-enhanced multislice spiral CT (MSCT) in judging the feasibility of excision of lung cancer. Methods The contrast-enhanced MSCT images of 68 patients with non-small cell lung cancer (NSCLC) diagnosed by operation or biopsy in our hospital from August 2014 to August 2016 in were retrospectively analyzed and were compared with results of operation. Results The coincidence rates of contrast-enhanced MSCT in evaluating pulmonary hilar and mediastinal great vessel invasion and mediastinal lymph node metastasis with the results of operation were 86.76% and 83.82%, the consistency was satisfying (Kappa=0.68, 0.61), the sensitivities were 77.78% and 80% respectively, the specificities were 90% and 86.05% respectively. The coincidence rate of contrast- enhanced MSCT in evaluating feasibility of excision of NSCLC with the results of operation was 79.41%, the consistency was satisfying (Kappa=0.57), sensitivity was 85.37%, and specificity was 70.37%. Conclusion Contrast-enhanced MSCT can reflect the invasion of blood vessels and mediastinal lymph node metastasis, providing objective data for the doctors to judge the resectability of NSCLC.

【关键词】肺癌;体层摄影技术;X线计 算机;淋巴结转移;可切除性

【中图分类号】R734.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2017.06.015

前言

肺癌是临床常见的恶性肿瘤之一,据报道2010年我国新发肺癌病 例高达60万例,且发病率仍呈逐年上升趋势[1]。非小细胞肺癌(NSCLC) 是肺癌最为常见的类型,早期NSCLC首选外科手术治疗,但T4N2~3 期非小细胞肺癌(NSCLC)、术前合并纵膈融合状肿大淋巴结、恶性胸 水等患者往往无法行手术治疗,以放化疗为主的全身治疗为主[2]。因 此,术前正确评估肿瘤分期,了解纵膈淋巴结转移、肿瘤侵犯器官等 情况,评估肺癌的可行除性,对临床确定治疗方案有重要指导意义。 多层螺旋CT(MSCT)具有扫描范围大、薄层扫描、后处理技术强大等特 点,可清楚显示肿瘤病灶、胸腔淋巴结、胸膜等解剖病理信息[3]。本 研究分析68例NSCLC患者增强MSCT影像学资料,评价有无纵膈淋巴结转 移、肿瘤周围大血管受侵等,旨在探讨MSCT对肺癌可切除性的预测价 值,现报道如下。