目的 探讨肝脾CT值比值与扩散 加权成像ADC值的相关性，研究扩散加权 成像ADC值对脂肪肝患者的严重程度分级 的可行性。方法 回顾性收集在我院影像 科检查的患者80例，所有的患者均行CT 和MRI扫描，包括正常对照组(n=20)、 轻度脂肪肝组(n=20)、中度脂肪肝组 (n=20）及重度脂肪肝组(n=20)。通过分 析肝脾CT值比值与ADC值的相关性及比 较四组样本的ADC值间的差异来评估ADC 值对脂肪肝患者的严重程度分级的可行 性。以P<0.05认为差异具有显著统计学 意义。结果 肝脾的CT值比值与ADC值之 间存在显著的正相关(r=0.954,P<0.05)； 肝 实 质 的 平 均 A D C 值 ： 正 常 肝 实 质 (1.451±0.123)×10-3mm2 /sec，轻度脂肪 肝(1.341±0.014)×10-3mm2 /sec，中度脂 肪肝(1.206±0.007)×10-3mm2 /sec，重度 脂肪肝(1.040±0.017)×10-3mm2 /sec， 组间比较差异均具有显著的统计学意义 (P<0.05)。结论 肝脾CT值比值与ADC值具 有显著正相关性，ADC值对肝细胞脂肪变 性的严重程度分级诊断是可行的。

Objective To explore the relationship between CT value of liver-to-spleen ratio and ADC value in the patients with fatty liver, and investigate the feasibility of ADC value in assessing hepatic steatosis grade of nonalcoholic fatty liver disease. Methods Eighty patients were analyzed retrospectively in this study, all the patients were performed CT and MRI examination, including normal group (n=20), mild fatty liver group (n=20), moderate group (n=20) and severe fatty liver group (n=20). The correlation analysis between CT value of liver-to-spleen ratio and ADC value was evaluated, and differences among four groups were also analyzed in this study. P<0.05 was considered as statistical significant difference. Results There was significant positively correlation between CT value of liver-to-spleen ratio and ADC value (r=0.954, P<0.05), and ADC value of liver parenchymal: normal group (1.451±0.123)×10-3mm2 /sec, mild fatty liver (1.341±0.014)×10-3mm2 /sec, moderate fatty liver (1.206±0.007)×10-3mm2 /sec, severe fatty liver (1.040±0.017)×10-3mm2 /sec, there was significant statistical difference among four groups (all P<0.05). Conclusion There was significant positively correlation between CT value of liver-to-spleen ratio and ADC value, ADC value could be available for evaluating hepatic steatosis grade of nonalcoholic fatty liver disease.