目的 研究脑外伤患者急性期 CT检查临床特征，及探讨其与血清NTproBNP相关性。方法 选取我院神经外科 收治的68例急性脑外伤患者。均经CT扫 描和血浆N端前脑钠肽水平检测，使用 Spearman软件分析相关性。结果 CT检查 发现，蛛网膜下腔出血患者、蛛网膜下 腔未出血患者血清N端前脑钠肽水平比 较，差异具有统计学意义(P＜0.05)； 重、中、轻度脑肿胀血清N端前脑钠 肽水平比较，差异具有统计学意义(P ＜0.05)；Ⅰ、Ⅱ、Ⅲ型脑外伤血清N端 前脑钠肽水平比较，差异具有统计学意 义(P＜0.05)。相关性分析结果显示，蛛 网膜下腔出血(r =6.78)、脑肿胀程度 (r=9.10)、脑出血CT分型(r=8.14)与血清 NT-proBNP呈正相关。结论 CT可反应脑外 伤患者蛛网膜下腔出血和脑肿胀情况，并 对脑外伤严重程度进行分型，上述临床指 标均与血清T-proBNP呈正相关，可根据 CT下患者脑损伤临床特征评估其血清NTproBNP水平，为临床操作与预后提供准确 依据。

Objective This paper is to investigate the clinical characteristics of CT examination on patients with traumatic brain injuries at acute stage and to explore its correlation with serum NT-proBNP. Methods Sixty eighty patients with acute traumatic brain injuries admitted by the Neurosurgery Department of the Hospital were selected. All patients underwent CT scanning and plasma NT-proBNP peptide level detections, and Spearman software was applied to analyze the correlation. Results The comparison in serum NT-proBNP peptide levels of patients with subarachnoid hemorrhage and no subarachnoid hemorrhage were significantly different(P<0.05). The difference of serum NT-proBNP peptide levels in patients with heavy, medium and mild brain swelling was significant (P<0.05). The difference of serum NT-proBNP peptide levels in patients of I, II and III stage traumatic brain injury was significant(P<0.05).The results of correlation analysis showed subarachnoid hemorrhage (r=6.78), cerebrum swelling degree (r=9.10) and CT classification of cerebral hemorrhage (r=8.14) were positively correlated to serum NT-proBNP. Conclusion CT is capable of reflecting subarachnoid hemorrhage in patients with traumatic brain injuries, brain swelling, making classification of brain injury. The above clinical indexes are positively correlated with serum T-proBNP, and the level of serum NT-proBNP may be evaluated according to the features of CT on patients with traumatic brain injuries, which provides accurate basis for clinical operations and prognosis.