目的 探讨3.0T磁共振扩散张量 成像对前列腺中央腺体区病变的鉴别诊断 价值。方法 分析行常规磁共振检查和扩 散张量成像检查并经病理证实的CZ-PCa 15例和BPH 20例、健康志愿者10例，分别 测量三组病例的表观扩散系数值和各向异 性值，观察三组之间的差异。运用种子点 法对病灶最大层面的纤维进行追踪，得到 DTT图，由2名高年资磁共振诊断医生采 用4级评分制对其进行评分，比较3组病 例纤维的走行、密度及连续性的差异。 结果 CZ-PCa组ADC值为(1026±176)×10- 6 mm2 /s、FA值为(0.46±0.02)×10-1；BPH 组ADC值为(1351±143)×10-6mm2 /s、FA 值为(0.23±0.04)×10-1；健康志愿者组 ADC值为(1458±188)×10-6mm2 /s、FA值为 (0.22±0.05)×10-1，3组间ADC值差异有 统计学意义(P<0.05)，FA值间差异无统 计学意义(P>0.05)。2名医师对3组DTT图 评分一致性较好(k=0.723)，CZ-PCa组评 分分别为2.8±0.9、2.9±0.4；BPH组为 1.6±0.8、1.7±0.42；健康志愿者组为 1±0.2、1±0.3。三组差异具有统计学意 义(P<0.05)。结论 在CG-PCa和BPH的鉴别 诊断中ADC值中具有重要价值，DTT图更能 直观地展现了前列腺纤维束，对两者的鉴 别具有一定的价值。

Objective To research the application value of 3.0T magnetic resonance diffusion tensor imaging in the central zone lesions of prostate. Methods Ten healthy volunteers, 15 CG-PCa cases and 20 BPH cases proven by histopathology were performed MRI and DTI. ADC values and FA values of CG-PCa and BPH were respectively measured, comparing whether there is any discrepancies among the three groups. For DTT maps, two observers recorded the score using a four-point scale and compared the differences of fibers continuity and density in the three groups. Results ADC values and FA values in CZ-PCa were: (1026±176)×10-6mm2 /s, (0.46±0.02)×10-1. BPH were(1351±143)×10-6mm2 /s, (0.23±0.04)×10-1, healthy volunteers were (1458±188)×10-6mm2 /s, (0.22±0.05)×10-1. ADC value of the three groups were statistically different(P<0.05)while FA values was not(P>0.05). The DTT map score of CZ-PCa were (2.8±0.9), (2.9±0.4), the BPH were (1.6±0.8), (1.7±0.42), healthy volunteers were T(1±0.2), (1±0.3). The consistency score of the three groups by two observers was good (k=0.723). The DTT map score between the three groups for two viewers were all significantly different(P<0.05). Conclusion ADC values can play a significant role in the differentiation of CG-PCa and BPH. DTT maps can show prostate fibers more Intuitively and it is helpful in differentiating PCa from BPH.