目的探讨宫颈癌化疗前后MRI影 像学变化对患者心理状态的影响及护理 干预措施。方法 选取经临床病理确诊为 宫颈癌患者57例，均接受新辅助化疗， 化疗前和化疗2个周期后行MR平扫和扩散 加权成像(DWI)。结果 化疗前DWI呈不均 匀高信号，对应ADC图像以蓝绿色区域为 主；化疗后，11例病灶无残留，DWI低信 号，对应ADC图蓝色区域减少；36例肿瘤 缩小，DWI高信号，ADC图以绿色或浅绿 色为主；9例DWI和ADC图与治疗前无明显 差异。有效组化疗后ADC值显著高于无效 组，症状自评量表(SCL-90)评分亚型显著 低于无效组(P＜0.05)。结论 DWI及ADC值 可预测宫颈癌肿瘤化疗效果，但影像学无 显著变化者会伴随出现负面情绪，需给予 积极护理干预。

Objective To explore effects of MRI imaging changes on the psychological status of patients with cervical cancer before and after chemotherapy and nursing intervention measures. Methods 57 cases of cervical cancer patients diagnosed by clinical pathology were selected, all patients underwent neo-adjuvant chemotherapy, MR plan scan and diffusion weighted imaging (DWI) were performed before and after 2 cycles of chemotherapy. Results DWI before chemotherapy was inhomogeneous high signals, the correlative ADC map was most in cyan area; after chemotherapy, 11 cases of lesions without residual, DWI low signal, blue area of the correlative ADC map reduced; 36 cases of decrease of tumor volume, DWI high signal, the correlative ADC map was most in green or reseda area, there was no significant difference between DWI and ADC map before and after treatment in 9 cases. After chemotherapy, ADC value in the effective group was significantly higher than the non-responders, score of symptom checklist 90 (SCL-90) subtype was significantly lower than non-responders (P＜0.05). Conclusion DWI and ADC value can predict the effect of chemotherapy on cervical cancer, but patients without significant imaging changes will be accompanied by negative emotions, and they need to be given active nursing intervention.