论著-头颈部
肾囊肿患者相关肾功能指标及CT征象变化研究*
作者:姜 燕1 臧秀娟1 王顺娟2 孙双权3
所属单位:1.上海市松江区中心医院肾内科 2.上海市松江区中心医院医学影像 诊断中心 3.上海市松江区中心医院泌尿外科 (上海 201600)
PDF摘要
目的 探讨肾囊肿和囊性小肾癌 患者肾功能指标差异,分析CT检查在两种 疾病鉴别诊断中的应用价值。方法 选取 204例单纯性肾囊肿患者(A组)及15例囊性 小肾癌患者(B组)为研究对象,均经手术 病理检查确诊;将同期入院体检的60例健 康志愿者纳入对照组,三组受试者均接受 肾功能检查,两研究组患者同时接受CT平 扫及增强扫描。对比三组肾功能指标差 异;以病理诊断结果为依据,评估CT检查 在囊性小肾癌和单纯性肾囊肿鉴别诊断中 的准确性。结果 三组受试者血清肌酐值 和血尿素氮检测结果显示对照组<研究A组 <研究B组,肾小球滤过率则显示对照组> 研究A组>研究B组(P<0.05);CT鉴别诊断 囊性小肾癌和单纯性肾囊肿的准确率为 85.8%(188/219),其中正确诊断单纯性肾 囊肿178例(87.3%,178/204),正确诊断囊 性小肾癌10例(66.7%,10/15)。结论 单纯 性肾囊肿和囊性小肾癌患者均存在肾功能 指标异常情况,需引起临床重视;两种疾 病的螺旋CT征象虽存在特异性,但在诊断 占位体积较小的病灶时仍具有漏诊、误诊 风险,建议将其可作为两疾病的辅助鉴别 诊断手段应用于临床诊疗工作中。
Objective To investigate the differences of renal function indexes between patients with renal cysts and cystic small renal cell carcinomas and to explore the application value of CT examination in the differential diagnosis of the two diseases. Methods Two hundred and four cases of patients with simple renal cysts (study group A) and 15 cases of patients with cystic small renal cell carcinoma (study groupB) were selected as the study subjects, and all of them were confirmed by operation and pathology. 60 healthy volunteers who received physical examination in the hospital during the same period were chosen as the control group. All the three groups received renal function examination. Patients in the two study groups received CT scan and enhanced scan at the same time. The renal function indexes were compared among the three groups; Based on the results of pathological diagnosis, the accuracy of CT examination in the differential diagnosis of cystic small renal cell carcinoma and simple renal cysts was evaluated. Results The detection results of SCr and BUN in the three groups of subjects show the control group < study group A < study group B while eGFR showed control group > study group A > study group B (P<0.05). The accuracy of CT in differential diagnosis of cystic small renal cell carcinoma and simple renal cysts was 85.8% (188/219), in which 178 cases (87.3%, 178/204) with simple renal cysts and 10 cases (66.7%,10/15) with cystic small renal cell carcinoma were diagnosed correctly. Conclusion Both of patients with simple renal cysts and cystic small cystic renal cell carcinoma have abnormal renal function indexes, which is worthy of attention; Although the spiral CT findings of the two diseases are specific, there are risks of missed diagnosis and misdiagnosis in the diagnosis of lesions with smaller occupied volume. It is suggested that CT can be used as an assisted differential diagnosis method in clinical diagnosis and treatment.
【关键词】肾囊肿;囊性小肾癌;肾功能;CT征象
【中图分类号】R445.3;R730.4
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.07.026
前言
肾囊肿是一种以50岁以上中老年人为主要患病群体的肾脏疾病, 可分为多种类型。单纯性肾囊肿作为临床最常见的类型之一,不同于 多囊肾等疾病可致终末期肾功能不全[1],故诊疗往往疏忽此类患者肾 功能的变化情况,从而影响治疗效果。CT作为当前诊断单纯性肾囊肿 最常见的影像技术之一,具有操作便利、无创、诊疗时间短、患者耐 受理想等优势[2],受到广泛认可。但部分学者仍认为,该检查技术难 以准确鉴别单纯性肾囊肿和囊性小肾癌[3],从而耽误最佳治疗时机, 于患者预后不利。本次研究分别选取204例确诊单纯性肾囊肿患者和15 例经病理检查确诊的囊性小肾癌患者为受试对象,旨在归纳分析CT在 两种疾病中的典型征象,以提高临床鉴别诊断准确性,现报告如下。
中国CT和MRI杂志
第14卷, 第 7 期
2016年07月
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