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冠脉CT造影对冠心病患者治疗与心血管病相关因素控制影响的研究

作者:刘玉茹1 卢艳秋2 徐慧敏1 杨克雅1

所属单位:1.河南大学淮河医院干部病房 (河南 开封 475000) 2.郑州大学第二附属医院ICU (河南 郑州 450000)

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摘要

目的 探讨冠状动脉CT造影对患 者的药物治疗和心血管病相关因素控制 的影响。方法 收集2015年1月至2016年1 月于我院心内科住院治疗的冠心病患者 200例,分为<70%狭窄组和≥70%狭窄 组,收集造影前基线资料,并对所有入 选患者进行随访,比较造影前后及两组 间心血管相关因素控制情况,比较造影 前后接受治疗情况。结果 狭窄<70% 组总胆固醇(-0.4±1.1)mmol/L、甘油 三酯(-0.4±0.4)mmol/L、低密度脂蛋 白胆固醇(-0.3±0.6)mmol/L和高密度 胆固醇(0.2±0.3)mmol/L改善程度,显 著优于狭窄≥70%组,差异有统计学意 义,P<0.05。冠脉CT造影后患者总胆固醇 (4.2±1.1)mmol/L、甘油三酯(1.8±0.4) mmol/L、低密度脂蛋白胆固醇(3.2±0.6) mmol/L和高密度胆固醇(1.2±0.3)mmol/ L,显著优于造影前相应指标,差异有统 计学意义,P<0.05;冠脉CT造影后患者收 缩压(138.2±3.8)mmHg较前降低,舒张压 (80.5±3.4)mmHg较前降低,差异有统计 学意义,P<0.05;冠脉CT造影后患者服用 硝酸酯类药物、调制药物、降压药物比例 分别为89.0%、91.0%和88.0%,较前显著 增高,差异有统计学意义,P<0.05。结论 冠状动脉CT造影结果可以增加冠心病患者 后续的药物治疗依从性,并对心血管病危 险因素控制有积极影响,具有重要临床价 值,值得推广。

Objective To investigate the effects of coronary CT angiography on the drug therapy and the control of cardiovascular risk factors in patients with coronary heart disease. Methods 200 cases of patients with coronary heart disease (CHD) methods in January 2015 to 2016 January hospitalized in the cardiology department of our hospital, divided into < 70% stenosis group and is equal to or more than 70% stenosis group collected contrast the baseline data, and to all the selected patients were followed up, before and after contrast and between the two groups of cardiovascular related factors control, before and after the angiography accepted treatment. Results stenosis < 70% group, the total cholesterol (-0.4+1.1) mmol / L, triglyceride (-0.4+0.4 mmol / L, low density lipoprotein cholesterol (-0.3+0.6) mmol / L and high density lipoprotein cholesterol (+0.2 0.3 mmol / L, the degree of improvement, was significantly better than that of the stenosis is more than or equal to 70% group, the difference is statistically significant, P<0.05. The proportion of relatively lower than before after contrastenhanced CT coronary angiography in patients after total cholesterol (1.8+0.4) mmol / L, triglyceride (4.2 L.L) mmol / L, low density lipoprotein cholesterol (3.2+0.6) mmol / L and high density lipoprotein cholesterol (1.2+0.3 mmol / L significantly better than the corresponding index, and the difference was statistically significant, P<0.05. Coronary CT angiography in patients with systolic pressure (138.2+3. 8) mmHg, diastolic blood pressure (80.5+3.4) mmHg lower, and the difference was statistically significant, P<0.05. Coronary CT angiography in patients taking nitrates drugs, modulation drugs, antihypertensive drugs were 89.0%, 91.0% and 88.0%, compared with the previous significantly increased, the difference was statistically significant, P<0.05. Conclusion Coronary CT angiography results can increase the follow-up of patients with coronary heart disease medication compliance, and cardiovascular risk factors control has a positive impact, has important clinical value, it is worth promoting.

【关键词】冠脉CT造影;冠心病;治疗; 心血管病相关因素

【中图分类号】R541.4;R445.3

【文献标识码】A

【DOI】10.3969/j.issn.1672- 5131.2016.07.017

前言

随着老龄化的发展,冠状动脉粥样硬化性心脏病 ( c o r o n a r y atherosclerotic heart disease,简称冠心病)发病率逐年增加,在 许多发达国家,冠心病排在死亡原因的第一位[1]。心血管相关危险因 素的控制和治疗是降低死亡率的有效方式,目前研究认为,冠状动脉 狭窄程度与后续治疗密切相关,因此明确冠脉狭窄程度十分重要[2-3]。 冠状动脉CT造影是诊断冠心病安全有效的技术,一直被认为是冠心病 诊断的“金标准”[4]。本研究旨在探讨冠状动脉CT造影对患者的药物 治疗和心血管病相关因素控制的影响,现报告如下。