目的 探讨256-CT下肢动脉造影 (256-multiple slice CT angiography, 256-MSCTA、彩色多普勒超声(doppuler ultra sound, DUS)、)两种方法在糖尿 病下肢血管病变(lower extremities arterial disease, LEAD)的中应用价 值。方法 50例DSA确诊2型糖尿病下肢 动脉病变患者，2周内行256-CTA及DUS检 查，分析DLEAD病变特点，各段血管以DSA 为金标准，计算两种检查方法敏感度、特 异度、阳性预测值、阴性预测值、诊断符 合率。结果 1.256-CTA 与DUS对下肢动脉 狭窄总体检出率无统计学差异(P>0.05)， 对膝下血管组阳性检出率256-CTA优于 DUS，差异有统计学意义(P<0.05)， 2.256-CTA在LEAD的评估中，与DSA对比灵 敏度、特异度、诊断符合率均较高。结论 256-CTA对糖尿病下肢动脉病变的诊断和 评估中，灵敏度、特异度较高，对膝下动 脉狭窄诊断优于DUS。

Objective To investigate the value of 256-multiple slice CT angiography and doppuler ultrasound in lower extremities arterial disease (LEAD). Methods 50 cases of type 2 diabetes diagnosed by DSA lower extremity arterial disease patients, underwent 256- CTA examination and DUS examination in two weeks.Analysis the imaging characteristics of the DLEAD,Each arteries with DSA as the gold standard, to calculate the sensitivity, specificity, positive predictive value, negative predictive value and the diagnosis rate of the two methods. Results 1.there was no significant difference on the overall detection rate of lower extremity arterial stenosis by 256-CTA and DUS(P>0.05). The sensitivity in observe vascular lesion under knee, using 256-CTA was better than using DUS,and the difference has statistical significance (P<0.01).2.Compared with DSA, 256-CTA in LEAD assessment, the sensitivity, specificity and diagnostic accuracy were similar. Conclusion 256-CTA method has high sensitivity and specificity in the diagnosis and evaluation of DLEAD. The application of 256-CTA is superior to DUS in Below the knee artery stenosis