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论著-头颈部

高血压脑微出血患者3.0T磁共振多序列诊断的价值*

作者:张 玉1 邹翠洁2 王成健1 杨景震1 霍英杰1 赵永强1 贺亚男1

所属单位:1.河北医科大学石油临床医学院中 国石油中心医院磁共振室 (河北 廊坊 065000) 2.廊坊卫生职业学院影像教研室 (河北 廊坊 065000)

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摘要

目的 探讨3.0T MR对高血压患 者脑微出血(CMBs)诊断的临床价值。方 法 对77例研究对象进行3.0TMR多序列 成像,并将其影像表现结合临床资料进 行分析。结果 40例患者CMBs病灶表现 为信号丢失,总数共计248个,SWI序列 与DWI序列的检出率差异有统计学意义 (χ2 =26.061,P<0.05)。DWI序列分别 与常规T2WI、T1WI序列检出率的差异 有统计学意义(χ2 =6.146,P=0.013; χ2 =17.802,P=0.000)。T2WI与T1WI序列 的检出率差异无统计学意义(χ2 =2.689, P=0.101)。结论 3.0T MR SWI联合常规MR 序列扫描技术明显提高了CMBs的检出率。

Objective To explore the clinic value of susceptibility weighted imaging (SWI) in patients with cerebral microbleeds (CMBs). Methods 3.0T MR multiple sequences imaging was used to examine 77 patents in this study. The imaging founding and related clinical data were analyzed. Results The CMBs lesions of 40 patients showed signal loss. The total CMBs number was 248. The difference of the detection rate between SWI and DWI was significant (χ2 =26.061, P<0.05). The detection rates differences between DWI sequence and conventional T2WI, T1WI sequence were significant (χ2 =6.146, P=0.013; χ2 =17.802, P=0.000). The detection rate of T2WI and T1WI sequence was not statistically significant (χ2 =2.689, P=0.101). Conclusions 3.0T MR SWI scanning technology combined with conventional MR sequences CMBs significantly improved the detection rate.

【关键词】脑微出血;磁敏感加权成像; 磁共振成像

【中图分类号】R445.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.06.004

前言

脑微出血(Cerebral microbleeds,CMBs)是脑小血管病的三 大表现之一,脑实质经常受到损害[1]。以前由于CMBs病变部位较 小,症状轻微,经常被忽视,延误治疗。现在随着磁敏感加权成像 (Susceptibility weighted imaging, SWI)序列的不断发展与应用, 微出血病变被大量有效的检出,SWI序列对含铁血黄素有极高的敏感 性,进而很好地显示微出血[2]。大量研究显示,CMBs与高血压等因素 密切相关,高血压可以引起脑微出血病灶的形成[3]。CMBs可以预知高 血压患者脑部微血管再次破裂出血的可能性及其位置[4]。本研究旨运 用3.0T磁共振磁多序列检测高血压患者颅内的脑微出血灶,比较不同 序列的敏感性,同时在与对照组比较时,对高血压患者脑微出血的发 生率及其分布进行探讨。