摘要
目的 将核磁共振以及超声应用 在胎儿的胼胝体发育不全筛选诊断中, 分析其诊断效果和影像学特征。方法 以 2011年1月至2015年1月间,30例经本院超 声、MRI检查后诊断为胼胝体发育不全的 胎儿为对象,对全部患者的病历资料进行 回顾分析,按照检查方法的不同进行组 别划分,将单纯接受超声检查的15例胼胝 体发育不全胎儿划分到对照组,将接受超 声联合核磁共振检查的15例胼胝体发育不 全胎儿划分至实验组;将两组胼胝体发育 不全胎儿的检查诊断结果和随访结果相比 较,对比两种检查方法的诊断准确率。 同时对胎儿胼胝体发育不全的超声影像 以及核磁共振影像进行分析。结果 实验 组胼胝体发育不全胎儿中,10例为胼胝 体完全缺如,5例为胼胝体部分缺如。实 验组的超声联合核磁共振诊断准确率为 93.3%(14/15)。对照组胼胝体发育不全胎 儿中,9例为胼胝体完全缺如,6例为胼胝 体部分缺如。对照组的超声诊断准确率为 86.7%(13/15)。可见实验组的诊断准确率 要显著高于对照组,且组间差异P<0.05。 结论 在产前对胎儿进行超声检查以及核 磁共振检查,能够有效提高胎儿胼胝体发 育不全的筛选诊断率,对胎儿胼胝体发育 不全的临床诊断有着非常重要的意义。
Objective To magnetic resonance imaging and ultrasonography in fetal agenesis of the corpus callosum screening diagnosis, analysis of the effect of diagnosis and imaging features. Methods By January 2011 to January 2015, 30 cases after the Institute of ultrasound and MRI diagnosis of corpus callosum of fetal development as the object, the medical records of all patients were retrospectively analyzed, divided into groups according to different methods to check will only accept ultrasonography of 15 cases of corpus callosum development whole fetuses divided to control group, will accept ultrasound combined with magnetic resonance imaging (MRI) of 15 patients with agenesis of the corpus callosum fetal divided to experiment group, two groups of corpus callosum body development not the fetal diagnosis results and follow-up results compared. Comparing the two kinds of inspection methods of diagnosis accurate rate. At the same time on the development of fetal corpus callosum ultrasound imaging insufficiency and magnetic resonance imaging analysis. Results The experimental group of fetal agenesis of the corpus callosum in 10 cases, 5 cases of complete agenesis of the corpus callosum, as part of the corpus callosum agenesis. The accuracy of diagnostic ultrasound and magnetic resonance of the experimental group was 93.3% (14/15). The control group of fetal agenesis of the corpus callosum in 9 cases, 6 cases of complete agenesis of the corpus callosum, as part of the corpus callosum agenesis. The diagnostic accuracy rate of control group was 86.7% (13/15). The accurate rate of diagnosis showed the experimental group was significantly higher than that of control group, and the difference of P<0.05 between groups. Conclusions In prenatal fetal of ultrasonography and magnetic resonance imaging (MRI) can effectively improve the fetal corpus callosum body development is full of screening and diagnosis rate, the clinical diagnosis of fetal corpus callosum development has a very important significance.
【关键词】胎儿胼胝体发育不全;超声; 核磁共振;
【中图分类号】R445.2;R714.5
【文献标识码】A
【DOI】 10.3969/j.issn.1672- 5131.2016.06.034
前言
胼胝体发育不全(ACC)属于胎儿神经系统畸形病症,由于胼胝体 主要形成于胎儿发育的第12周至20周期间,因此,胎儿胼胝体发育不 全的筛查诊断适合在20周以后才进行[1]。目前,临床上通常采取超声 诊断方式来对胎儿胼胝体发育不全进行筛选[2]。但是单独进行超声检 查,对胎儿胼胝体发育不全的临床筛选诊断效果不是很理想,因此, 还有待作进一步的研究。笔者以近年在本院接受胼胝体发育不全筛选 检查的30例胎儿为对象,研究核磁共振联合超声对胎儿胼胝体发育不 全的临床应用效果,并且分析其影像学特征,现整理报告如下。
中国CT和MRI杂志
第14卷, 第 6 期
2016年06月
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