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膀胱癌的PETCT显像诊断价值研究

作者:于 洋

所属单位:河北大学附属医院泌尿外科(河北 保定 071000)

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摘要

目的 研究18F-FDG PETCT显像对 膀胱癌的诊断价值。方法 选取我院核医 学科2013年3月-2015年2月收治的34例可 疑膀胱癌患者,术前分别采用增强CT和 18F-FDG PETCT显像进行诊断,通过参考手 术病理结果回顾性分析18F-FDG PETCT显像 诊断的效果。结果 该34例经手术病理观 察均确诊为移行细胞癌,增强CT、18F-FDG PETCT显像诊断准确度分别为91.18%、 94.12%,差异无统计学意义(P<0.05);术 中共有11例膀胱肿瘤出现盆腔淋巴结或 邻近组织转移、浸润,18F-FDG PETCT显 像诊断准确度为72.73%,明显高于增强 CT(27.27%),具有统计学意义(P<0.05)。 结论 18F-FDG PETCT显像和增强CT均是 临床诊断膀胱癌的有效方法,但18F-FDG PETCT显像在观察膀胱肿瘤病灶的转移和 对邻近组织的浸润效果较好,对指导临床 诊断和了解肿瘤病变具有重要参考价值。

Objective To study the value of 18F-FDG PETCT imaging in the diagnosis of bladder cancer. Methods 34 cases of patients with suspected bladder cancer who were admitted in the department of nuclear medicine of our hospital between March 2013 and February 2015 were included in the study. Before operation, the patients were diagnosed by enhanced CT and 18F-FDG PETCT imaging respectively. The effect of 18F-FDG PETCT imaging diagnosis was retrospectively analyzed with reference to the pathological results. Results All the 34 cases were diagnosed as transitional cell carcinoma by operation and pathology. The diagnostic accuracy rates of enhanced CT and 18F-FDG PETCT imaging were 91.18% and 94.12%, respectively (P<0.05). There were 11 cases of bladder tumors with presence of pelvic lymph nodes or adjacent tissue metastasis and infiltration. The accuracy of 18F-FDG PETCT imaging diagnosis (72.73%) was significantly higher than that of the enhanced CT (27.27%) (P<0.05). Conclusions Both of 18F-FDG PETCT imaging and enhanced CT are effective methods for the clinical diagnosis of bladder cancer, but 18F-FDG PET-CT imaging is better at observing bladder tumor metastasis and adjacent tissue infiltration. It is of important reference value in guiding the clinical diagnosis and understanding of the neoplastic lesions.

【关键词】膀胱癌;18F-FDG PETCT;增强CT

【中图分类号】R737.14

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.06.028

前言

膀胱癌作为泌尿系统最为常见的恶性肿瘤疾病,多发于男性,肿 瘤多来自于上皮组织且易发生转移,早期及时诊断对疾病治疗和改善 预后至关重要[1]。随着正电子发射断层显像/X射线断层扫描技术(PET/ CT)的发展和完善,现已成为恶性肿瘤疾病早期诊断、病情跟踪和疗 效预后评估的重要方法[2]。我院于2013年3月~2015年2月对收治的34 例膀胱癌患者分别行增强CT和18F-FDG PETCT显像诊断,发现18F-FDG PETCT显像取得较好的诊断效果,具体报告如下。