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胸部CT平扫、灌注成像对中央型肺癌诊断及分型的价值

作者:马金勇

所属单位:山东省东营市人民医院放射科(山东 东营 257091)

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摘要

目的 探讨胸部CT平扫、灌注成 像对中央型肺癌早期诊断及分型的准确 性。方法 选择我院2011年3月-2015年10 月收治69例中央型肺癌患者作为研究对 象,均行胸部CT平扫、灌注成像,总结 早期中央型肺癌胸部CT平扫表现,计算诊 断符合率并与病理结果比较,对比不同 分型患者灌注指标。结果 肺门区可见团 块状或结节状软组织密度病变,大小在 20mm×19mm~50mm×21mm,边缘均不规 则,见毛刺30例、分叶状32例。肺段支气 管狭窄33例、闭塞29例。CT平扫联合灌注 成像诊断结果为39例鳞癌、23例腺癌,诊 断与分型符合率为89.9%(62/69),与病 理结果的差异P﹥0.05,准确性较高。结论 胸部CT平扫联合灌注成像可观察中央型肺 癌患者肺部病变形态、边缘、密度,显示 病变与支气管、纵隔关系及纵隔淋巴结转 移情况,利于早期诊断及分型。

Objective To investigate the accuracy rates of chest CT scan and perfusion imaging in early diagnosis and typing of central lung cancer. Methods 69 cases of patients with central lung cancer who were admitted in our hospital between March 2011 and October 2015 were selected as study subjects. Chest CT scan and perfusion imaging were performed. The CT scan findings of early central lung cancer were summarized. The diagnostic coincidence rate was calculated and was compared with the pathological results. The perfusion indexes in patients of different types were compared. Results There were lumpy or nodular soft tissue density lesions in hilar region, size in 20mm×19mm~ 50mm x 21mm, with irregular edges, presence of sentus in 30 cases and lobulated ones in 32 cases. There were pulmonary segmental bronchial stenosis in 33 cases and occlusion in 29 cases. The findings of CT plain scan combined with perfusion imaging were 39 cases with squamous cell carcinomas and 23 cases with adenocarcinomas. The coincidence rate of diagnosis and typing was 89.9% (62/69), and the difference from the pathological results was significant (P>0.05), which indicated that the accuracy was relatively higher. Conclusions Chest CT scan combined with perfusion imaging can be used to observe the shape, edge and density of central lung cancer lesions, to showed the correlation between lesions and bronchus and mediastinum as well as the status of lymph node metastasis. It is conducive to early diagnosis and typing

【关键词】中央型肺癌;早期诊断;CT平扫;灌注成像;分型

【中图分类号】R734.2

【文献标识码】A

【DOI】 10.3969/j.issn.1672- 5131.2016.06.015

前言

随着生活方式的改变及居住环境的恶化,肺癌成为威胁人类生 命健康的常见恶性肿瘤,有资料显示[1],全球每年肺癌新增患者约为 160万,在恶性肿瘤中所占比例约13%,而每年死于肺癌的人数则达 140 万,死亡率居恶性肿瘤之首。早期中央型肺癌患者癌组织未超过 三级支气管壁范围,周围肺实质不受侵犯且无淋巴结转移[2]。患者多 症状不明显,发现时多已发展至中晚期,5年生存率低于15%。有研究 发现[3],及早发现小于3cm且局限于肺内的肺癌,5年生存率可升高至 60%。可见,早发现早诊断为肺癌预后改善的关键。本研究以我院收治 中央型肺癌患者为例,探析胸部CT平扫、灌注成像对中央型肺癌早期 诊断及分型的准确性,现报道如下。